Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACOT7Acyl-CoA thioesterase 7. (380 aa)    
Predicted Functional Partners:
ACOT2
ACOT2 isoform 1.
    
 0.941
BAAT
Bile acid-CoA:amino acid N-acyltransferase.
    
 0.936
ACOT4
ACOT4 isoform 1.
    
 0.936
THEM4
Thioesterase superfamily member 4.
     
 0.930
THEM5
Thioesterase superfamily member 5.
     
 0.930
TECR
TECR isoform 2.
     
 0.928
MBLAC2
Metallo-beta-lactamase domain containing 2.
  
 
  0.902
ACOT13
Acyl-coenzyme A thioesterase 13, N-terminally processed; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA (in vitro) (By similarity). May play a role in controlling adaptive thermogenesis (By similarity).
   
 
 0.659
SCNN1D
SCNN1D isoform 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.632
CR201_G0025659
GPR153 isoform 1.
    
 
 0.569
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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