| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COMMD2 | USP6NL | ENSPPYP00000015880 | ENSPPYP00000002419 | COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. | USP6 N-terminal like. | 0.492 |
| ECHDC3 | PAFAH2 | ENSPPYP00000002421 | ENSPPYP00000001964 | ECHDC3 isoform 2. | Platelet-activating factor acetylhydrolase. | 0.486 |
| ECHDC3 | USP6NL | ENSPPYP00000002421 | ENSPPYP00000002419 | ECHDC3 isoform 2. | USP6 N-terminal like. | 0.486 |
| EPS8 | RAB5A | ENSPPYP00000004948 | ENSPPYP00000015744 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | RAB5A, member RAS oncogene family. | 0.473 |
| EPS8 | USP6NL | ENSPPYP00000004948 | ENSPPYP00000002419 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | USP6 N-terminal like. | 0.590 |
| FAM214B | RHNO1 | ENSPPYP00000021404 | ENSPPYP00000004737 | Protein FAM214B; Belongs to the FAM214 family. | RAD9-HUS1-RAD1 interacting nuclear orphan 1. | 0.568 |
| FAM214B | USP6NL | ENSPPYP00000021404 | ENSPPYP00000002419 | Protein FAM214B; Belongs to the FAM214 family. | USP6 N-terminal like. | 0.489 |
| PAFAH2 | ECHDC3 | ENSPPYP00000001964 | ENSPPYP00000002421 | Platelet-activating factor acetylhydrolase. | ECHDC3 isoform 2. | 0.486 |
| PAFAH2 | USP6NL | ENSPPYP00000001964 | ENSPPYP00000002419 | Platelet-activating factor acetylhydrolase. | USP6 N-terminal like. | 0.485 |
| RAB19 | USP6NL | ENSPPYP00000020260 | ENSPPYP00000002419 | RAB19 isoform 1. | USP6 N-terminal like. | 0.942 |
| RAB5A | EPS8 | ENSPPYP00000015744 | ENSPPYP00000004948 | RAB5A, member RAS oncogene family. | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | 0.473 |
| RAB5A | RABGEF1 | ENSPPYP00000015744 | ENSPPYP00000019637 | RAB5A, member RAS oncogene family. | RABGEF1 isoform 2. | 0.996 |
| RAB5A | USP6NL | ENSPPYP00000015744 | ENSPPYP00000002419 | RAB5A, member RAS oncogene family. | USP6 N-terminal like. | 0.526 |
| RABGEF1 | RAB5A | ENSPPYP00000019637 | ENSPPYP00000015744 | RABGEF1 isoform 2. | RAB5A, member RAS oncogene family. | 0.996 |
| RABGEF1 | USP6NL | ENSPPYP00000019637 | ENSPPYP00000002419 | RABGEF1 isoform 2. | USP6 N-terminal like. | 0.468 |
| RHNO1 | FAM214B | ENSPPYP00000004737 | ENSPPYP00000021404 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. | Protein FAM214B; Belongs to the FAM214 family. | 0.568 |
| RHNO1 | USP6NL | ENSPPYP00000004737 | ENSPPYP00000002419 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. | USP6 N-terminal like. | 0.487 |
| USP6NL | COMMD2 | ENSPPYP00000002419 | ENSPPYP00000015880 | USP6 N-terminal like. | COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. | 0.492 |
| USP6NL | ECHDC3 | ENSPPYP00000002419 | ENSPPYP00000002421 | USP6 N-terminal like. | ECHDC3 isoform 2. | 0.486 |
| USP6NL | EPS8 | ENSPPYP00000002419 | ENSPPYP00000004948 | USP6 N-terminal like. | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | 0.590 |
