Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FAM171A1Protein FAM171A1; Involved in the regulation of the cytoskeletal dynamics, plays a role in actin stress fiber formation. (890 aa)    
Predicted Functional Partners:
UNKL
UNKL isoform 6.
      
 0.887
ADGRA3
ADGRA3 isoform 1; Belongs to the G-protein coupled receptor 2 family.
      
 0.887
CAMKK1
CAMKK1 isoform 1.
      
 0.886
SMTN
SMTN isoform 1.
      
 0.849
KDM6B
KDM6B isoform 2.
   
  
 0.802
CERK
Ceramide kinase.
      
 0.766
TNFRSF10D
Uncharacterized protein.
      
 0.765
KHNYN
KHNYN isoform 1.
      
 0.667
DUSP6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.514
BRINP2
BMP/retinoic acid-inducible neural-specific protein 2; Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition; Belongs to the BRINP family.
      
 0.510
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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