| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DNMT3B | TRDMT1 | ENSPPYP00000012188 | ENSPPYP00000002461 | DNMT3B isoform 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | TRDMT1 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.688 |
| METTL1 | NSUN2 | ENSPPYP00000005363 | ENSPPYP00000023868 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.890 |
| METTL1 | NSUN6 | ENSPPYP00000005363 | ENSPPYP00000002478 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | NSUN6 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.553 |
| METTL1 | TRDMT1 | ENSPPYP00000005363 | ENSPPYP00000002461 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | TRDMT1 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.862 |
| METTL1 | TRMT10A | ENSPPYP00000005363 | ENSPPYP00000016695 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | TRMT10A isoform 1. | 0.791 |
| METTL1 | TRMT10B | ENSPPYP00000005363 | ENSPPYP00000021357 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | TRMT10B isoform 2. | 0.791 |
| METTL1 | TRMT10C | ENSPPYP00000005363 | ENSPPYP00000015196 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | TRMT10C isoform 1. | 0.826 |
| METTL1 | TRMT11 | ENSPPYP00000005363 | ENSPPYP00000019024 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA (guanine(10)-N2)-methyltransferase homolog; Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs. | 0.860 |
| METTL1 | TRMT12 | ENSPPYP00000005363 | ENSPPYP00000021167 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA methyltransferase 12 homolog. | 0.406 |
| NSUN2 | METTL1 | ENSPPYP00000023868 | ENSPPYP00000005363 | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.890 |
| NSUN2 | NSUN6 | ENSPPYP00000023868 | ENSPPYP00000002478 | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NSUN6 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.826 |
| NSUN2 | TRDMT1 | ENSPPYP00000023868 | ENSPPYP00000002461 | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | TRDMT1 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.762 |
| NSUN2 | TRMT10A | ENSPPYP00000023868 | ENSPPYP00000016695 | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | TRMT10A isoform 1. | 0.572 |
| NSUN2 | TRMT10B | ENSPPYP00000023868 | ENSPPYP00000021357 | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | TRMT10B isoform 2. | 0.572 |
| NSUN2 | TRMT10C | ENSPPYP00000023868 | ENSPPYP00000015196 | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | TRMT10C isoform 1. | 0.568 |
| NSUN2 | TRMT11 | ENSPPYP00000023868 | ENSPPYP00000019024 | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine(10)-N2)-methyltransferase homolog; Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs. | 0.592 |
| NSUN2 | TRMT12 | ENSPPYP00000023868 | ENSPPYP00000021167 | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA methyltransferase 12 homolog. | 0.509 |
| NSUN6 | METTL1 | ENSPPYP00000002478 | ENSPPYP00000005363 | NSUN6 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.553 |
| NSUN6 | NSUN2 | ENSPPYP00000002478 | ENSPPYP00000023868 | NSUN6 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.826 |
| NSUN6 | TRDMT1 | ENSPPYP00000002478 | ENSPPYP00000002461 | NSUN6 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | TRDMT1 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.696 |
