STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)    
Predicted Functional Partners:
SEMA3A
SEMA3A isoform 1; Belongs to the semaphorin family.
    
 0.999
L1CAM
L1 cell adhesion molecule.
    
 0.998
PLXNA4
PLXNA4 isoform 2.
    
 0.997
PLXNA2
PLXNA2 isoform 1.
    
 0.996
PLXNA1
PLXNA1 isoform 1.
    
 0.996
KDR
Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.991
SEMA3C
Semaphorin-3C; Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).
  
 
 0.987
SEMA3F
SEMA3F isoform 4; Belongs to the semaphorin family.
    
 0.985
SEMA3D
SEMA3D isoform 1; Belongs to the semaphorin family.
    
 0.985
SEMA3E
SEMA3E isoform 1; Belongs to the semaphorin family.
  
 
 0.985
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.