SAR1A protein (Pongo abelii) - STRING interaction network

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SAR1A

GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). (198 aa)

Predicted Functional Partners:

SEC23B

0.998

PREB

0.994

SEC13

0.987

SEC31B

0.978

SEC23A

0.946

SEC31A

0.937

SAR1B

0.936

SEC24B

0.936

SEC24A

0.934

SEC24C

0.886

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PREB	SAR1A	ENSPPYP00000014030	ENSPPYP00000002755	Prolactin regulatory element binding.	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	0.994
PREB	SAR1B	ENSPPYP00000014030	ENSPPYP00000017655	Prolactin regulatory element binding.	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.	0.994
PREB	SEC13	ENSPPYP00000014030	ENSPPYP00000015269	Prolactin regulatory element binding.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.789
PREB	SEC23A	ENSPPYP00000014030	ENSPPYP00000006547	Prolactin regulatory element binding.	Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.799
PREB	SEC23B	ENSPPYP00000014030	ENSPPYP00000012004	Prolactin regulatory element binding.	Protein transport protein Sec23B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.	0.771
PREB	SEC24A	ENSPPYP00000014030	ENSPPYP00000017656	Prolactin regulatory element binding.	SEC24 homolog A, COPII coat complex component.	0.814
PREB	SEC24B	ENSPPYP00000014030	ENSPPYP00000024040	Prolactin regulatory element binding.	SEC24B isoform 3.	0.858
PREB	SEC24C	ENSPPYP00000014030	ENSPPYP00000002707	Prolactin regulatory element binding.	SEC24C isoform 1.	0.709
PREB	SEC31A	ENSPPYP00000014030	ENSPPYP00000016625	Prolactin regulatory element binding.	Protein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).	0.696
PREB	SEC31B	ENSPPYP00000014030	ENSPPYP00000002982	Prolactin regulatory element binding.	LOW QUALITY PROTEIN: protein transport protein Sec31B.	0.419
SAR1A	PREB	ENSPPYP00000002755	ENSPPYP00000014030	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	Prolactin regulatory element binding.	0.994
SAR1A	SAR1B	ENSPPYP00000002755	ENSPPYP00000017655	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.	0.936
SAR1A	SEC13	ENSPPYP00000002755	ENSPPYP00000015269	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.987
SAR1A	SEC23A	ENSPPYP00000002755	ENSPPYP00000006547	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.946
SAR1A	SEC23B	ENSPPYP00000002755	ENSPPYP00000012004	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	Protein transport protein Sec23B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.	0.998
SAR1A	SEC24A	ENSPPYP00000002755	ENSPPYP00000017656	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	SEC24 homolog A, COPII coat complex component.	0.934
SAR1A	SEC24B	ENSPPYP00000002755	ENSPPYP00000024040	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	SEC24B isoform 3.	0.936
SAR1A	SEC24C	ENSPPYP00000002755	ENSPPYP00000002707	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	SEC24C isoform 1.	0.886
SAR1A	SEC31A	ENSPPYP00000002755	ENSPPYP00000016625	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	Protein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).	0.937
SAR1A	SEC31B	ENSPPYP00000002755	ENSPPYP00000002982	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).	LOW QUALITY PROTEIN: protein transport protein Sec31B.	0.978

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