STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANK3ANK3 isoform 1. (4275 aa)    
Predicted Functional Partners:
CR201_G0043999
SPTBN4 isoform 1.
   
 0.972
ITPR3
ITPR3 isoform 1.
    
 0.958
TIAM1
TIAM1 isoform 1.
    
 0.945
GABARAP
Gamma-aminobutyric acid receptor-associated protein-like 1; Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family.
   
 
 0.944
ANK1
Ankyrin-1 isoform X1.
     
0.928
ITPR1
ITPR1 isoform 3.
    
 0.926
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
    
 0.910
NFASC
NFASC isoform 1.
   
 0.904
CR201_G0015864
EPB41 isoform 1.
   
  
 0.884
SPTBN1
Spectrin beta chain; Belongs to the spectrin family.
   
 0.881
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.