| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DKK1 | DKK2 | ENSPPYP00000002828 | ENSPPYP00000016733 | Dickkopf-like protein 1. | DKK2 isoform 3. | 0.972 |
| DKK1 | DKK4 | ENSPPYP00000002828 | ENSPPYP00000020807 | Dickkopf-like protein 1. | Dickkopf WNT signaling pathway inhibitor 4. | 0.952 |
| DKK1 | KREMEN1 | ENSPPYP00000002828 | ENSPPYP00000013030 | Dickkopf-like protein 1. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.951 |
| DKK1 | KREMEN2 | ENSPPYP00000002828 | ENSPPYP00000007942 | Dickkopf-like protein 1. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.869 |
| DKK1 | LRP6 | ENSPPYP00000002828 | ENSPPYP00000024153 | Dickkopf-like protein 1. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.998 |
| DKK1 | WNT1 | ENSPPYP00000002828 | ENSPPYP00000005109 | Dickkopf-like protein 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.876 |
| DKK1 | WNT2B | ENSPPYP00000002828 | ENSPPYP00000001192 | Dickkopf-like protein 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.857 |
| DKK1 | WNT3 | ENSPPYP00000002828 | ENSPPYP00000009317 | Dickkopf-like protein 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.886 |
| DKK1 | WNT3A | ENSPPYP00000002828 | ENSPPYP00000000148 | Dickkopf-like protein 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.931 |
| DKK1 | WNT6 | ENSPPYP00000002828 | ENSPPYP00000014734 | Dickkopf-like protein 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.863 |
| DKK2 | DKK1 | ENSPPYP00000016733 | ENSPPYP00000002828 | DKK2 isoform 3. | Dickkopf-like protein 1. | 0.972 |
| DKK2 | DKK4 | ENSPPYP00000016733 | ENSPPYP00000020807 | DKK2 isoform 3. | Dickkopf WNT signaling pathway inhibitor 4. | 0.943 |
| DKK2 | KREMEN1 | ENSPPYP00000016733 | ENSPPYP00000013030 | DKK2 isoform 3. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.759 |
| DKK2 | KREMEN2 | ENSPPYP00000016733 | ENSPPYP00000007942 | DKK2 isoform 3. | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. | 0.565 |
| DKK2 | LRP6 | ENSPPYP00000016733 | ENSPPYP00000024153 | DKK2 isoform 3. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.986 |
| DKK2 | WNT1 | ENSPPYP00000016733 | ENSPPYP00000005109 | DKK2 isoform 3. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.787 |
| DKK2 | WNT2B | ENSPPYP00000016733 | ENSPPYP00000001192 | DKK2 isoform 3. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.852 |
| DKK2 | WNT3 | ENSPPYP00000016733 | ENSPPYP00000009317 | DKK2 isoform 3. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.784 |
| DKK2 | WNT3A | ENSPPYP00000016733 | ENSPPYP00000000148 | DKK2 isoform 3. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.846 |
| DKK2 | WNT6 | ENSPPYP00000016733 | ENSPPYP00000014734 | DKK2 isoform 3. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.865 |
