STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)    
Predicted Functional Partners:
OAT
OAT isoform 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.998
GLUD1
Glutamate dehydrogenase 1; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.989
GLUD2
Glutamate dehydrogenase 2, mitochondrial.
    
 0.989
ALDH4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.988
GLS
GLS isoform 1.
    
 0.980
GLS2
GLS2 isoform 5.
    
 0.979
GMPS
GMP synthase [glutamine-hydrolyzing].
  
 
 0.955
GLUL
Glutamine synthetase.
    
 0.917
FDXR
NADPH:adrenodoxin oxidoreductase, mitochondrial.
    
 0.916
FADS6
FADS6 isoform 1.
    
 0.916
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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