Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM160B1FAM160B1 isoform 2. (711 aa)    
Predicted Functional Partners:
HOOK1
Hook microtubule tethering protein 1.
    
 
 0.755
PALD1
PALD1 isoform 1.
      
 0.726
FAM124A
Protein FAM124A; Belongs to the FAM124 family.
      
 0.658
FAM160A1
Family with sequence similarity 160 member A1.
    
 
 0.658
HOOK3
Protein Hook homolog 3 isoform X1.
    
 
 0.611
AKTIP
AKT-interacting protein; Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade (By similarity).
    
 
 0.573
TNFSF13B
Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family.
    
   0.554
HOOK2
Hook microtubule tethering protein 2.
    
 
 0.529
INTS10
Integrator complex subunit 10.
      
 0.487
TRUB1
TRUB1 isoform 1.
      
 0.485
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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