| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0002531 | CR201_G0024663 | ENSPPYP00000010106 | ENSPPYP00000013134 | TXNDC2 isoform 4. | TXN2 isoform 1. | 0.539 |
| CR201_G0002531 | NME8 | ENSPPYP00000010106 | ENSPPYP00000019759 | TXNDC2 isoform 4. | NME8 isoform 1. | 0.535 |
| CR201_G0002531 | PRDX1 | ENSPPYP00000010106 | ENSPPYP00000001637 | TXNDC2 isoform 4. | PRDX1 isoform 2. | 0.860 |
| CR201_G0002531 | PRDX3 | ENSPPYP00000010106 | ENSPPYP00000003152 | TXNDC2 isoform 4. | Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.774 |
| CR201_G0002531 | PRDX5 | ENSPPYP00000010106 | ENSPPYP00000003590 | TXNDC2 isoform 4. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.804 |
| CR201_G0024663 | CR201_G0002531 | ENSPPYP00000013134 | ENSPPYP00000010106 | TXN2 isoform 1. | TXNDC2 isoform 4. | 0.539 |
| CR201_G0024663 | ENSPPYP00000016598 | ENSPPYP00000013134 | ENSPPYP00000016598 | TXN2 isoform 1. | annotation not available | 0.632 |
| CR201_G0024663 | NME8 | ENSPPYP00000013134 | ENSPPYP00000019759 | TXN2 isoform 1. | NME8 isoform 1. | 0.663 |
| CR201_G0024663 | PRDX1 | ENSPPYP00000013134 | ENSPPYP00000001637 | TXN2 isoform 1. | PRDX1 isoform 2. | 0.820 |
| CR201_G0024663 | PRDX3 | ENSPPYP00000013134 | ENSPPYP00000003152 | TXN2 isoform 1. | Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.983 |
| CR201_G0024663 | PRDX5 | ENSPPYP00000013134 | ENSPPYP00000003590 | TXN2 isoform 1. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.938 |
| CR201_G0024663 | TXN | ENSPPYP00000013134 | ENSPPYP00000021834 | TXN2 isoform 1. | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] | 0.539 |
| ENSPPYP00000016598 | CR201_G0024663 | ENSPPYP00000016598 | ENSPPYP00000013134 | annotation not available | TXN2 isoform 1. | 0.632 |
| ENSPPYP00000016598 | NME8 | ENSPPYP00000016598 | ENSPPYP00000019759 | annotation not available | NME8 isoform 1. | 0.413 |
| ENSPPYP00000016598 | PRDX1 | ENSPPYP00000016598 | ENSPPYP00000001637 | annotation not available | PRDX1 isoform 2. | 0.942 |
| ENSPPYP00000016598 | PRDX3 | ENSPPYP00000016598 | ENSPPYP00000003152 | annotation not available | Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.774 |
| ENSPPYP00000016598 | PRDX5 | ENSPPYP00000016598 | ENSPPYP00000003590 | annotation not available | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.804 |
| ENSPPYP00000016598 | TXN | ENSPPYP00000016598 | ENSPPYP00000021834 | annotation not available | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] | 0.900 |
| LRRK2 | PRDX3 | ENSPPYP00000023875 | ENSPPYP00000003152 | LRRK2 isoform 3. | Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.767 |
| NDUFS1 | PRDX3 | ENSPPYP00000014646 | ENSPPYP00000003152 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By sim [...] | Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.885 |
