FAM53B protein (Pongo abelii) - STRING interaction network

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Score

FAM53B

Family with sequence similarity 53 member B. (422 aa)

Predicted Functional Partners:

DYRK1B

0.803

CYFIP2

0.656

SFN

0.637

YWHAE

0.634

DYRK1A

0.554

ENSPPYP00000000181

0.532

CNIH2

0.532

GLO1

0.513

YWHAB

0.469

ENSPPYP00000019656

0.440

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNIH2	FAM53B	ENSPPYP00000003506	ENSPPYP00000003201	Cornichon family AMPA receptor auxiliary protein 2.	Family with sequence similarity 53 member B.	0.532
CNIH2	GLO1	ENSPPYP00000003506	ENSPPYP00000018532	Cornichon family AMPA receptor auxiliary protein 2.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.422
CYFIP2	FAM53B	ENSPPYP00000017891	ENSPPYP00000003201	Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).	Family with sequence similarity 53 member B.	0.656
DYRK1A	DYRK1B	ENSPPYP00000012738	ENSPPYP00000011170	DYRK1A isoform 7.	Dual specificity tyrosine phosphorylation regulated kinase 1B.	0.889
DYRK1A	ENSPPYP00000019656	ENSPPYP00000012738	ENSPPYP00000019656	DYRK1A isoform 7.	annotation not available	0.464
DYRK1A	FAM53B	ENSPPYP00000012738	ENSPPYP00000003201	DYRK1A isoform 7.	Family with sequence similarity 53 member B.	0.554
DYRK1A	YWHAB	ENSPPYP00000012738	ENSPPYP00000012330	DYRK1A isoform 7.	14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...]	0.900
DYRK1A	YWHAE	ENSPPYP00000012738	ENSPPYP00000008753	DYRK1A isoform 7.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.	0.591
DYRK1B	DYRK1A	ENSPPYP00000011170	ENSPPYP00000012738	Dual specificity tyrosine phosphorylation regulated kinase 1B.	DYRK1A isoform 7.	0.889
DYRK1B	FAM53B	ENSPPYP00000011170	ENSPPYP00000003201	Dual specificity tyrosine phosphorylation regulated kinase 1B.	Family with sequence similarity 53 member B.	0.803
DYRK1B	YWHAB	ENSPPYP00000011170	ENSPPYP00000012330	Dual specificity tyrosine phosphorylation regulated kinase 1B.	14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...]	0.644
ENSPPYP00000000181	FAM53B	ENSPPYP00000000181	ENSPPYP00000003201	annotation not available	Family with sequence similarity 53 member B.	0.532
ENSPPYP00000000181	GLO1	ENSPPYP00000000181	ENSPPYP00000018532	annotation not available	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.422
ENSPPYP00000019656	DYRK1A	ENSPPYP00000019656	ENSPPYP00000012738	annotation not available	DYRK1A isoform 7.	0.464
ENSPPYP00000019656	FAM53B	ENSPPYP00000019656	ENSPPYP00000003201	annotation not available	Family with sequence similarity 53 member B.	0.440
ENSPPYP00000019656	SFN	ENSPPYP00000019656	ENSPPYP00000001937	annotation not available	SFN isoform 1; Belongs to the 14-3-3 family.	0.932
ENSPPYP00000019656	YWHAB	ENSPPYP00000019656	ENSPPYP00000012330	annotation not available	14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...]	0.972
FAM53B	CNIH2	ENSPPYP00000003201	ENSPPYP00000003506	Family with sequence similarity 53 member B.	Cornichon family AMPA receptor auxiliary protein 2.	0.532
FAM53B	CYFIP2	ENSPPYP00000003201	ENSPPYP00000017891	Family with sequence similarity 53 member B.	Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).	0.656
FAM53B	DYRK1A	ENSPPYP00000003201	ENSPPYP00000012738	Family with sequence similarity 53 member B.	DYRK1A isoform 7.	0.554