| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTBP1 | CTBP2 | ENSPPYP00000016231 | ENSPPYP00000003207 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | CTBP2 isoform 10. | 0.997 |
| CTBP1 | HDAC1 | ENSPPYP00000016231 | ENSPPYP00000001838 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.992 |
| CTBP1 | HDAC2 | ENSPPYP00000016231 | ENSPPYP00000018964 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Histone deacetylase 2. | 0.959 |
| CTBP1 | LEF1 | ENSPPYP00000016231 | ENSPPYP00000016739 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Lymphoid enhancer binding factor 1. | 0.943 |
| CTBP1 | MECOM | ENSPPYP00000016231 | ENSPPYP00000015958 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | MDS1 and EVI1 complex locus. | 0.982 |
| CTBP1 | RBPJ | ENSPPYP00000016231 | ENSPPYP00000016373 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Recombining binding protein suppressor of hairless; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling [...] | 0.913 |
| CTBP1 | RUNX1 | ENSPPYP00000016231 | ENSPPYP00000012719 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.923 |
| CTBP1 | TCF7 | ENSPPYP00000016231 | ENSPPYP00000017648 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | TCF7 isoform 6. | 0.946 |
| CTBP1 | ZEB1 | ENSPPYP00000016231 | ENSPPYP00000002549 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Zinc finger E-box binding homeobox 1. | 0.976 |
| CTBP1 | ZNF217 | ENSPPYP00000016231 | ENSPPYP00000012448 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | ZNF217 isoform 1. | 0.951 |
| CTBP2 | CTBP1 | ENSPPYP00000003207 | ENSPPYP00000016231 | CTBP2 isoform 10. | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.997 |
| CTBP2 | HDAC1 | ENSPPYP00000003207 | ENSPPYP00000001838 | CTBP2 isoform 10. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.939 |
| CTBP2 | HDAC2 | ENSPPYP00000003207 | ENSPPYP00000018964 | CTBP2 isoform 10. | Histone deacetylase 2. | 0.837 |
| CTBP2 | LEF1 | ENSPPYP00000003207 | ENSPPYP00000016739 | CTBP2 isoform 10. | Lymphoid enhancer binding factor 1. | 0.942 |
| CTBP2 | MECOM | ENSPPYP00000003207 | ENSPPYP00000015958 | CTBP2 isoform 10. | MDS1 and EVI1 complex locus. | 0.951 |
| CTBP2 | RBPJ | ENSPPYP00000003207 | ENSPPYP00000016373 | CTBP2 isoform 10. | Recombining binding protein suppressor of hairless; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling [...] | 0.913 |
| CTBP2 | RUNX1 | ENSPPYP00000003207 | ENSPPYP00000012719 | CTBP2 isoform 10. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.913 |
| CTBP2 | TCF7 | ENSPPYP00000003207 | ENSPPYP00000017648 | CTBP2 isoform 10. | TCF7 isoform 6. | 0.946 |
| CTBP2 | ZEB1 | ENSPPYP00000003207 | ENSPPYP00000002549 | CTBP2 isoform 10. | Zinc finger E-box binding homeobox 1. | 0.908 |
| CTBP2 | ZNF217 | ENSPPYP00000003207 | ENSPPYP00000012448 | CTBP2 isoform 10. | ZNF217 isoform 1. | 0.828 |
