| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDX54 | OPN5 | ENSPPYP00000005686 | ENSPPYP00000018662 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | OPN5 isoform 2; Belongs to the G-protein coupled receptor 1 family. | 0.516 |
| DDX54 | PDPK1 | ENSPPYP00000005686 | ENSPPYP00000007927 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | PDPK1 isoform 1. | 0.490 |
| DDX54 | SLC9A8 | ENSPPYP00000005686 | ENSPPYP00000012424 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.401 |
| DDX54 | STK32C | ENSPPYP00000005686 | ENSPPYP00000003239 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | Serine/threonine kinase 32C; Belongs to the protein kinase superfamily. | 0.557 |
| DRD2 | STK32C | ENSPPYP00000004451 | ENSPPYP00000003239 | DRD2 isoform 2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine kinase 32C; Belongs to the protein kinase superfamily. | 0.555 |
| MAPKAP1 | MLST8 | ENSPPYP00000021975 | ENSPPYP00000007913 | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | MTOR associated protein, LST8 homolog. | 0.996 |
| MAPKAP1 | PDPK1 | ENSPPYP00000021975 | ENSPPYP00000007927 | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | PDPK1 isoform 1. | 0.425 |
| MAPKAP1 | RICTOR | ENSPPYP00000021975 | ENSPPYP00000017219 | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | RICTOR isoform 1. | 0.999 |
| MAPKAP1 | RPTOR | ENSPPYP00000021975 | ENSPPYP00000024617 | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | RPTOR isoform 4. | 0.873 |
| MAPKAP1 | STK32C | ENSPPYP00000021975 | ENSPPYP00000003239 | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | Serine/threonine kinase 32C; Belongs to the protein kinase superfamily. | 0.611 |
| MAPKAP1 | TSC2 | ENSPPYP00000021975 | ENSPPYP00000007907 | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | TSC2 isoform 1. | 0.498 |
| MLST8 | MAPKAP1 | ENSPPYP00000007913 | ENSPPYP00000021975 | MTOR associated protein, LST8 homolog. | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | 0.996 |
| MLST8 | PDPK1 | ENSPPYP00000007913 | ENSPPYP00000007927 | MTOR associated protein, LST8 homolog. | PDPK1 isoform 1. | 0.669 |
| MLST8 | RICTOR | ENSPPYP00000007913 | ENSPPYP00000017219 | MTOR associated protein, LST8 homolog. | RICTOR isoform 1. | 0.995 |
| MLST8 | RPTOR | ENSPPYP00000007913 | ENSPPYP00000024617 | MTOR associated protein, LST8 homolog. | RPTOR isoform 4. | 0.999 |
| MLST8 | STK32C | ENSPPYP00000007913 | ENSPPYP00000003239 | MTOR associated protein, LST8 homolog. | Serine/threonine kinase 32C; Belongs to the protein kinase superfamily. | 0.567 |
| MLST8 | TSC2 | ENSPPYP00000007913 | ENSPPYP00000007907 | MTOR associated protein, LST8 homolog. | TSC2 isoform 1. | 0.866 |
| OPN5 | DDX54 | ENSPPYP00000018662 | ENSPPYP00000005686 | OPN5 isoform 2; Belongs to the G-protein coupled receptor 1 family. | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | 0.516 |
| OPN5 | SLC9A8 | ENSPPYP00000018662 | ENSPPYP00000012424 | OPN5 isoform 2; Belongs to the G-protein coupled receptor 1 family. | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.722 |
| OPN5 | STK32C | ENSPPYP00000018662 | ENSPPYP00000003239 | OPN5 isoform 2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine kinase 32C; Belongs to the protein kinase superfamily. | 0.731 |