STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PWWP2BPWWP2B isoform 1. (624 aa)    
Predicted Functional Partners:
TMEM251
T0119592 isoform 3.
      
 0.750
TAF5L
TAF5L isoform 1.
      
 0.727
ZMYM2
Zinc finger MYM-type protein 2; May function as a transcription factor.
      
 0.582
KRTAP4-8
Keratin associated protein 4-8.
      
 0.582
BRD4
Bromodomain containing 4.
    
 
 0.557
C2orf68
Chromosome 2 open reading frame 68.
      
 0.497
RBBP4
Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...]
    
 
 0.477
REG4
REG4 isoform 1.
      
 0.457
KDM5C
KDM5C isoform 2.
      
 0.446
BRD2
BRD2 isoform 1.
    
 
 0.435
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.