| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | ALDH4A1 | ENSPPYP00000002911 | ENSPPYP00000002085 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.991 |
| ALDH18A1 | CPS1 | ENSPPYP00000002911 | ENSPPYP00000014680 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Carbamoyl-phosphate synthase 1. | 0.703 |
| ALDH18A1 | GLS | ENSPPYP00000002911 | ENSPPYP00000014554 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | GLS isoform 1. | 0.967 |
| ALDH18A1 | GLS2 | ENSPPYP00000002911 | ENSPPYP00000005314 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | GLS2 isoform 5. | 0.967 |
| ALDH18A1 | GLUD1 | ENSPPYP00000002911 | ENSPPYP00000003292 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamate dehydrogenase 1; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.983 |
| ALDH18A1 | GLUD2 | ENSPPYP00000002911 | ENSPPYP00000023161 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamate dehydrogenase 2, mitochondrial. | 0.983 |
| ALDH18A1 | GLUL | ENSPPYP00000002911 | ENSPPYP00000000500 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamine synthetase. | 0.910 |
| ALDH18A1 | GOT2 | ENSPPYP00000002911 | ENSPPYP00000008377 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.483 |
| ALDH18A1 | PC | ENSPPYP00000002911 | ENSPPYP00000003482 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.590 |
| ALDH4A1 | ALDH18A1 | ENSPPYP00000002085 | ENSPPYP00000002911 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.991 |
| ALDH4A1 | GLS | ENSPPYP00000002085 | ENSPPYP00000014554 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | GLS isoform 1. | 0.913 |
| ALDH4A1 | GLS2 | ENSPPYP00000002085 | ENSPPYP00000005314 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | GLS2 isoform 5. | 0.926 |
| ALDH4A1 | GLUD1 | ENSPPYP00000002085 | ENSPPYP00000003292 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate dehydrogenase 1; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.962 |
| ALDH4A1 | GLUD2 | ENSPPYP00000002085 | ENSPPYP00000023161 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate dehydrogenase 2, mitochondrial. | 0.959 |
| ALDH4A1 | GLUL | ENSPPYP00000002085 | ENSPPYP00000000500 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamine synthetase. | 0.939 |
| ALDH4A1 | GOT1L1 | ENSPPYP00000002085 | ENSPPYP00000020754 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.938 |
| ALDH4A1 | GOT2 | ENSPPYP00000002085 | ENSPPYP00000008377 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.942 |
| CPS1 | ALDH18A1 | ENSPPYP00000014680 | ENSPPYP00000002911 | Carbamoyl-phosphate synthase 1. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.703 |
| CPS1 | GLS | ENSPPYP00000014680 | ENSPPYP00000014554 | Carbamoyl-phosphate synthase 1. | GLS isoform 1. | 0.918 |
| CPS1 | GLS2 | ENSPPYP00000014680 | ENSPPYP00000005314 | Carbamoyl-phosphate synthase 1. | GLS2 isoform 5. | 0.918 |
