Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CR201_G0054731T0193459 isoform 3. (473 aa)    
Predicted Functional Partners:
ALG14
ALG14 UDP-N-acetylglucosaminyltransferase subunit.
   
  
 0.534
RAPSN
Receptor associated protein of the synapse.
   
  
 0.519
PREPL
Prolyl endopeptidase-like; Serine peptidase whose precise substrate specificity remains unclear (By similarity). Does not cleave peptides after a arginine or lysine residue (By similarity). Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex (By similarity). May play a role in the regulation of synaptic vesicle exocytosis (By similarity).
      
 0.510
COLQ
Collagen like tail subunit of asymmetric acetylcholinesterase.
      
 0.504
ITSN2
ITSN2 isoform 3.
     
 0.493
GMPPB
GDP-mannose pyrophosphorylase B.
    
 
 0.491
DPAGT1
DPAGT1 isoform 1.
      
 0.486
STON2
STON2 isoform 2; Belongs to the Stoned B family.
   
 0.483
VAMP1
Vesicle associated membrane protein 1.
    
 0.476
DNM3
DNM3 isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.474
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (18%) [HD]