DHTKD1 protein (Pongo abelii) - STRING interaction network

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAT	DHTKD1	ENSPPYP00000016979	ENSPPYP00000003298	Aminoadipate aminotransferase.	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.938
AADAT	GCDH	ENSPPYP00000016979	ENSPPYP00000010777	Aminoadipate aminotransferase.	GCDH isoform 3.	0.421
CS	DBT	ENSPPYP00000005303	ENSPPYP00000001294	Citrate synthase, mitochondrial isoform X1.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.799
CS	DHTKD1	ENSPPYP00000005303	ENSPPYP00000003298	Citrate synthase, mitochondrial isoform X1.	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.813
CS	DLD	ENSPPYP00000005303	ENSPPYP00000020072	Citrate synthase, mitochondrial isoform X1.	Dihydrolipoyl dehydrogenase, mitochondrial; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched- chain amino acid-dehydrogenase complex). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT [...]	0.908
CS	DLST	ENSPPYP00000005303	ENSPPYP00000006812	Citrate synthase, mitochondrial isoform X1.	Dihydrolipoamide S-succinyltransferase.	0.909
CS	ENSPPYP00000024659	ENSPPYP00000005303	ENSPPYP00000024659	Citrate synthase, mitochondrial isoform X1.	2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).	0.909
CS	SUCLA2	ENSPPYP00000005303	ENSPPYP00000006097	Citrate synthase, mitochondrial isoform X1.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.928
CS	SUCLG1	ENSPPYP00000005303	ENSPPYP00000013652	Citrate synthase, mitochondrial isoform X1.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.933
DBT	CS	ENSPPYP00000001294	ENSPPYP00000005303	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Citrate synthase, mitochondrial isoform X1.	0.799
DBT	DHTKD1	ENSPPYP00000001294	ENSPPYP00000003298	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.778
DBT	DLD	ENSPPYP00000001294	ENSPPYP00000020072	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoyl dehydrogenase, mitochondrial; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched- chain amino acid-dehydrogenase complex). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT [...]	0.996
DBT	DLST	ENSPPYP00000001294	ENSPPYP00000006812	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide S-succinyltransferase.	0.603
DBT	ENSPPYP00000024659	ENSPPYP00000001294	ENSPPYP00000024659	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).	0.607
DBT	GCDH	ENSPPYP00000001294	ENSPPYP00000010777	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	GCDH isoform 3.	0.435
DBT	SUCLA2	ENSPPYP00000001294	ENSPPYP00000006097	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.678
DBT	SUCLG1	ENSPPYP00000001294	ENSPPYP00000013652	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.795
DHTKD1	AADAT	ENSPPYP00000003298	ENSPPYP00000016979	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	Aminoadipate aminotransferase.	0.938
DHTKD1	CS	ENSPPYP00000003298	ENSPPYP00000005303	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	Citrate synthase, mitochondrial isoform X1.	0.813
DHTKD1	DBT	ENSPPYP00000003298	ENSPPYP00000001294	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.778