STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF7IRF7 isoform 12. (396 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.998
IRAK1
Interleukin 1 receptor associated kinase 1.
   
 0.990
IRF3
IRF3 isoform 6.
   
0.987
IRAK4
IRAK4 isoform 6.
   
 0.984
TBK1
TANK binding kinase 1.
   
 0.983
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.981
EP300
EP300 isoform 1.
    
 0.979
IFNB1
Interferon beta 1.
   
 
 0.977
CHUK
CHUK isoform 1.
    
 0.973
CREBBP
CREBBP isoform 1.
    
 0.969
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.