CD151 protein (Pongo abelii) - STRING interaction network

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD151	CMTM6	ENSPPYP00000003360	ENSPPYP00000015709	Tetraspanin.	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	0.736
CD151	DNAH1	ENSPPYP00000003360	ENSPPYP00000015453	Tetraspanin.	DNAH1 isoform 1.	0.765
CD151	GRAMD1C	ENSPPYP00000003360	ENSPPYP00000015133	Tetraspanin.	Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...]	0.813
CD151	INVS	ENSPPYP00000003360	ENSPPYP00000021789	Tetraspanin.	INVS isoform 2.	0.767
CD151	ITGA3	ENSPPYP00000003360	ENSPPYP00000010024	Tetraspanin.	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	0.941
CD151	ITGA6	ENSPPYP00000003360	ENSPPYP00000014440	Tetraspanin.	ITGA6 isoform 6; Belongs to the integrin alpha chain family.	0.879
CD151	ITGB1	ENSPPYP00000003360	ENSPPYP00000002560	Tetraspanin.	Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...]	0.896
CD151	ITGB4	ENSPPYP00000003360	ENSPPYP00000009696	Tetraspanin.	Integrin beta.	0.912
CD151	PTGFRN	ENSPPYP00000003360	ENSPPYP00000001141	Tetraspanin.	PTGFRN isoform 1.	0.812
CD151	SPDEF	ENSPPYP00000003360	ENSPPYP00000018471	Tetraspanin.	SPDEF isoform 2.	0.740
CMTM6	CD151	ENSPPYP00000015709	ENSPPYP00000003360	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	Tetraspanin.	0.736
CMTM6	DNAH1	ENSPPYP00000015709	ENSPPYP00000015453	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	DNAH1 isoform 1.	0.891
CMTM6	INVS	ENSPPYP00000015709	ENSPPYP00000021789	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	INVS isoform 2.	0.859
DNAH1	CD151	ENSPPYP00000015453	ENSPPYP00000003360	DNAH1 isoform 1.	Tetraspanin.	0.765
DNAH1	CMTM6	ENSPPYP00000015453	ENSPPYP00000015709	DNAH1 isoform 1.	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	0.891
DNAH1	INVS	ENSPPYP00000015453	ENSPPYP00000021789	DNAH1 isoform 1.	INVS isoform 2.	0.889
GRAMD1C	CD151	ENSPPYP00000015133	ENSPPYP00000003360	Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...]	Tetraspanin.	0.813
INVS	CD151	ENSPPYP00000021789	ENSPPYP00000003360	INVS isoform 2.	Tetraspanin.	0.767
INVS	CMTM6	ENSPPYP00000021789	ENSPPYP00000015709	INVS isoform 2.	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	0.859
INVS	DNAH1	ENSPPYP00000021789	ENSPPYP00000015453	INVS isoform 2.	DNAH1 isoform 1.	0.889