STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOLLIPToll interacting protein. (274 aa)    
Predicted Functional Partners:
IRAK1
Interleukin 1 receptor associated kinase 1.
   
 0.985
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.982
TLR2
Toll-like receptor.
    
 0.980
TOM1
TOM1 isoform 6; Belongs to the TOM1 family.
    
 
 0.975
IRAK4
IRAK4 isoform 6.
   
 0.964
TOM1L2
TOM1L2 isoform 8; Belongs to the TOM1 family.
    
 
 0.899
TOM1L1
TOM1L1 isoform 12; Belongs to the TOM1 family.
    
 
 0.886
TIRAP
TIR domain containing adaptor protein.
     
 0.879
IL1R1
Interleukin 1 receptor type 1.
    
 0.855
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.820
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.