| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL | CH25H | ENSPPYP00000022270 | ENSPPYP00000002851 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | 0.810 |
| CEL | CYP7A1 | ENSPPYP00000022270 | ENSPPYP00000020869 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.813 |
| CEL | DHCR24 | ENSPPYP00000022270 | ENSPPYP00000001525 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | DHCR24 isoform 1. | 0.902 |
| CEL | DHCR7 | ENSPPYP00000022270 | ENSPPYP00000003422 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | DHCR7 isoform 1. | 0.901 |
| CEL | LIPA | ENSPPYP00000022270 | ENSPPYP00000002852 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.912 |
| CH25H | CEL | ENSPPYP00000002851 | ENSPPYP00000022270 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.810 |
| CH25H | CYP7A1 | ENSPPYP00000002851 | ENSPPYP00000020869 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.968 |
| CH25H | DHCR24 | ENSPPYP00000002851 | ENSPPYP00000001525 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | DHCR24 isoform 1. | 0.912 |
| CH25H | DHCR7 | ENSPPYP00000002851 | ENSPPYP00000003422 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | DHCR7 isoform 1. | 0.946 |
| CH25H | LIPA | ENSPPYP00000002851 | ENSPPYP00000002852 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.828 |
| CH25H | LSS | ENSPPYP00000002851 | ENSPPYP00000012870 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.748 |
| CH25H | SC5D | ENSPPYP00000002851 | ENSPPYP00000004558 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.905 |
| CH25H | SOAT1 | ENSPPYP00000002851 | ENSPPYP00000000531 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | O-acyltransferase. | 0.845 |
| CH25H | SOAT2 | ENSPPYP00000002851 | ENSPPYP00000005210 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | O-acyltransferase. | 0.845 |
| CH25H | SQLE | ENSPPYP00000002851 | ENSPPYP00000021174 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | SQLE isoform 1. | 0.949 |
| CYP7A1 | CEL | ENSPPYP00000020869 | ENSPPYP00000022270 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.813 |
| CYP7A1 | CH25H | ENSPPYP00000020869 | ENSPPYP00000002851 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | 0.968 |
| CYP7A1 | DHCR24 | ENSPPYP00000020869 | ENSPPYP00000001525 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | DHCR24 isoform 1. | 0.888 |
| CYP7A1 | DHCR7 | ENSPPYP00000020869 | ENSPPYP00000003422 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | DHCR7 isoform 1. | 0.910 |
| CYP7A1 | LIPA | ENSPPYP00000020869 | ENSPPYP00000002852 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | Lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.857 |
