Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CPT1ACPT1A isoform 3; Belongs to the carnitine/choline acetyltransferase family. (526 aa)    
Predicted Functional Partners:
ACACB
ACACB isoform 1.
     
 0.957
CPT2
Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family.
  
 
0.925
CPT1B
Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family.
  
  
0.921
CPT1C
CPT1C isoform 2; Belongs to the carnitine/choline acetyltransferase family.
  
  
 
0.907
ACSL1
ACSL1 isoform 4.
   
 
 0.811
ACSL5
ACSL5 isoform 4.
   
 
 0.774
ACSL3
Long-chain-fatty-acid--CoA ligase 3; Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta- oxidation (By similarity). ACSL3 is required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins) (By similarity). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity [...]
   
 
 0.767
PPARA
Peroxisome proliferator activated receptor alpha.
    
 0.760
ACSL4
ACSL4 isoform 2.
   
 
 0.725
ACSL6
T0008628 isoform 1.
   
 
 0.713
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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