| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATR | CLSPN | ENSPPYP00000015853 | ENSPPYP00000001791 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | CLSPN isoform 4. | 0.924 |
| ATR | ENSPPYP00000020452 | ENSPPYP00000015853 | ENSPPYP00000020452 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | annotation not available | 0.803 |
| ATR | HUS1 | ENSPPYP00000015853 | ENSPPYP00000023458 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | Checkpoint protein; Belongs to the HUS1 family. | 0.979 |
| ATR | HUS1B | ENSPPYP00000015853 | ENSPPYP00000018080 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | Checkpoint protein; Belongs to the HUS1 family. | 0.785 |
| ATR | RAD1 | ENSPPYP00000015853 | ENSPPYP00000017189 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | Cell cycle checkpoint protein RAD1; Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavag [...] | 0.989 |
| ATR | RAD17 | ENSPPYP00000015853 | ENSPPYP00000017352 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | Cell cycle checkpoint protein RAD17; Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination (By similarity); Belongs to the rad17/RAD24 family. | 0.973 |
| ATR | RAD9A | ENSPPYP00000015853 | ENSPPYP00000003473 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | Cell cycle checkpoint control protein; Belongs to the rad9 family. | 0.991 |
| ATR | RAD9B | ENSPPYP00000015853 | ENSPPYP00000005650 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | Cell cycle checkpoint control protein; Belongs to the rad9 family. | 0.981 |
| ATR | RFC2 | ENSPPYP00000015853 | ENSPPYP00000019603 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | RFC2 isoform 5. | 0.824 |
| ATR | TOPBP1 | ENSPPYP00000015853 | ENSPPYP00000015789 | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | TOPBP1 isoform 1. | 0.983 |
| CLSPN | ATR | ENSPPYP00000001791 | ENSPPYP00000015853 | CLSPN isoform 4. | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | 0.924 |
| CLSPN | ENSPPYP00000020452 | ENSPPYP00000001791 | ENSPPYP00000020452 | CLSPN isoform 4. | annotation not available | 0.538 |
| CLSPN | HUS1 | ENSPPYP00000001791 | ENSPPYP00000023458 | CLSPN isoform 4. | Checkpoint protein; Belongs to the HUS1 family. | 0.538 |
| CLSPN | HUS1B | ENSPPYP00000001791 | ENSPPYP00000018080 | CLSPN isoform 4. | Checkpoint protein; Belongs to the HUS1 family. | 0.508 |
| CLSPN | RAD17 | ENSPPYP00000001791 | ENSPPYP00000017352 | CLSPN isoform 4. | Cell cycle checkpoint protein RAD17; Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination (By similarity); Belongs to the rad17/RAD24 family. | 0.877 |
| CLSPN | RAD9A | ENSPPYP00000001791 | ENSPPYP00000003473 | CLSPN isoform 4. | Cell cycle checkpoint control protein; Belongs to the rad9 family. | 0.929 |
| CLSPN | RAD9B | ENSPPYP00000001791 | ENSPPYP00000005650 | CLSPN isoform 4. | Cell cycle checkpoint control protein; Belongs to the rad9 family. | 0.781 |
| CLSPN | RFC2 | ENSPPYP00000001791 | ENSPPYP00000019603 | CLSPN isoform 4. | RFC2 isoform 5. | 0.695 |
| CLSPN | TOPBP1 | ENSPPYP00000001791 | ENSPPYP00000015789 | CLSPN isoform 4. | TOPBP1 isoform 1. | 0.971 |
| ENSPPYP00000020452 | ATR | ENSPPYP00000020452 | ENSPPYP00000015853 | annotation not available | ATR isoform 1; Belongs to the PI3/PI4-kinase family. | 0.803 |
