EFEMP2 protein (Pongo abelii) - STRING interaction network

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Score

EFEMP2

EFEMP2 isoform 1. (442 aa)

Predicted Functional Partners:

LOX

0.816

CR201_G0032167

0.748

ATP6V0A2

0.686

ADAMTS2

0.662

FBN1

0.661

MFAP2

0.640

MFAP5

0.628

PYCR1

0.582

FKBP10

0.571

ADAMTS4

0.562

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS2	ATP6V0A2	ENSPPYP00000018034	ENSPPYP00000005803	ADAMTS2 isoform 2.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.588
ADAMTS2	EFEMP2	ENSPPYP00000018034	ENSPPYP00000003523	ADAMTS2 isoform 2.	EFEMP2 isoform 1.	0.662
ADAMTS2	FBN1	ENSPPYP00000018034	ENSPPYP00000007315	ADAMTS2 isoform 2.	FBN1 isoform 1.	0.592
ADAMTS2	LOX	ENSPPYP00000018034	ENSPPYP00000023654	ADAMTS2 isoform 2.	LOX isoform 1.	0.602
ADAMTS2	PYCR1	ENSPPYP00000018034	ENSPPYP00000009827	ADAMTS2 isoform 2.	Pyrroline-5-carboxylate reductase 1, mitochondrial; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress. Belongs to the pyrroline-5-carboxylate reductase family.	0.457
ADAMTS4	ATP6V0A2	ENSPPYP00000000708	ENSPPYP00000005803	A disintegrin and metalloproteinase with thrombospondin motifs 4; Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-\|- Ala-393' site.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.502
ADAMTS4	CR201_G0032167	ENSPPYP00000000708	ENSPPYP00000014983	A disintegrin and metalloproteinase with thrombospondin motifs 4; Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-\|- Ala-393' site.	FBLN2 isoform 1.	0.422
ADAMTS4	EFEMP2	ENSPPYP00000000708	ENSPPYP00000003523	A disintegrin and metalloproteinase with thrombospondin motifs 4; Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-\|- Ala-393' site.	EFEMP2 isoform 1.	0.562
ADAMTS4	FBN1	ENSPPYP00000000708	ENSPPYP00000007315	A disintegrin and metalloproteinase with thrombospondin motifs 4; Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-\|- Ala-393' site.	FBN1 isoform 1.	0.488
ADAMTS4	LOX	ENSPPYP00000000708	ENSPPYP00000023654	A disintegrin and metalloproteinase with thrombospondin motifs 4; Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-\|- Ala-393' site.	LOX isoform 1.	0.481
ATP6V0A2	ADAMTS2	ENSPPYP00000005803	ENSPPYP00000018034	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ADAMTS2 isoform 2.	0.588
ATP6V0A2	ADAMTS4	ENSPPYP00000005803	ENSPPYP00000000708	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	A disintegrin and metalloproteinase with thrombospondin motifs 4; Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-\|- Ala-393' site.	0.502
ATP6V0A2	EFEMP2	ENSPPYP00000005803	ENSPPYP00000003523	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	EFEMP2 isoform 1.	0.686
ATP6V0A2	LOX	ENSPPYP00000005803	ENSPPYP00000023654	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	LOX isoform 1.	0.535
ATP6V0A2	PYCR1	ENSPPYP00000005803	ENSPPYP00000009827	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Pyrroline-5-carboxylate reductase 1, mitochondrial; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress. Belongs to the pyrroline-5-carboxylate reductase family.	0.616
CR201_G0032167	ADAMTS4	ENSPPYP00000014983	ENSPPYP00000000708	FBLN2 isoform 1.	A disintegrin and metalloproteinase with thrombospondin motifs 4; Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-\|- Ala-393' site.	0.422
CR201_G0032167	EFEMP2	ENSPPYP00000014983	ENSPPYP00000003523	FBLN2 isoform 1.	EFEMP2 isoform 1.	0.748
CR201_G0032167	FBN1	ENSPPYP00000014983	ENSPPYP00000007315	FBLN2 isoform 1.	FBN1 isoform 1.	0.782
CR201_G0032167	MFAP2	ENSPPYP00000014983	ENSPPYP00000002107	FBLN2 isoform 1.	MFAP2 isoform 3.	0.669
CR201_G0032167	MFAP5	ENSPPYP00000014983	ENSPPYP00000004839	FBLN2 isoform 1.	Microfibril associated protein 5.	0.595