Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SNX15SNX15 isoform 1. (336 aa)    
Predicted Functional Partners:
REEP6
Receptor accessory protein 6.
    
 
 0.753
REEP5
Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors.
    
   0.749
RINT1
RINT1 isoform 1.
   
 0.748
USE1
Unconventional SNARE in the endoplasmic reticulum protein 1.
    
 0.745
STX18
Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
   
 0.744
RTN4
Reticulon.
    
   0.736
ZW10
Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (By similarity).
   
 0.729
NBAS
NBAS isoform 1.
    
 0.721
VWA5A
VWA5A isoform 1.
    
 
 0.663
TMEM63C
Calcium permeable stress-gated cation channel 1.
      
 0.657
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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