| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATG2A | ATG2B | ENSPPYP00000003576 | ENSPPYP00000006962 | ATG2A isoform 1. | ATG2B isoform 1. | 0.907 |
| ATG2A | ATG9A | ENSPPYP00000003576 | ENSPPYP00000014748 | ATG2A isoform 1. | Autophagy-related protein 9A; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H (By similarity). | 0.902 |
| ATG2A | ATG9B | ENSPPYP00000003576 | ENSPPYP00000020385 | ATG2A isoform 1. | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. | 0.769 |
| ATG2A | CR201_G0024013 | ENSPPYP00000003576 | ENSPPYP00000009631 | ATG2A isoform 1. | WIPI1 isoform 2. | 0.968 |
| ATG2A | EHD1 | ENSPPYP00000003576 | ENSPPYP00000003578 | ATG2A isoform 1. | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary v [...] | 0.730 |
| ATG2A | ENSPPYP00000009167 | ENSPPYP00000003576 | ENSPPYP00000009167 | ATG2A isoform 1. | annotation not available | 0.977 |
| ATG2A | ULK1 | ENSPPYP00000003576 | ENSPPYP00000005848 | ATG2A isoform 1. | Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. | 0.969 |
| ATG2A | ULK2 | ENSPPYP00000003576 | ENSPPYP00000009920 | ATG2A isoform 1. | Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. | 0.976 |
| ATG2A | WDR45B | ENSPPYP00000003576 | ENSPPYP00000009860 | ATG2A isoform 1. | WD repeat domain phosphoinositide-interacting protein 3; Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Binds phosphatidylinositol 3-phosphate (PtdIns3P) forming on membranes of the endoplasmic reticulum upon activation of the upstream ULK1 and PI3 kinases and is recruited at phagophore assembly sites where it regulates the elongation of nascent phagophores downstream of WIPI2. In the cellular response to starvation, may also functi [...] | 0.977 |
| ATG2A | WIPI2 | ENSPPYP00000003576 | ENSPPYP00000019420 | ATG2A isoform 1. | WIPI2 isoform 1. | 0.981 |
| ATG2B | ATG2A | ENSPPYP00000006962 | ENSPPYP00000003576 | ATG2B isoform 1. | ATG2A isoform 1. | 0.907 |
| ATG2B | ATG9A | ENSPPYP00000006962 | ENSPPYP00000014748 | ATG2B isoform 1. | Autophagy-related protein 9A; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H (By similarity). | 0.745 |
| ATG2B | ATG9B | ENSPPYP00000006962 | ENSPPYP00000020385 | ATG2B isoform 1. | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. | 0.742 |
| ATG2B | CR201_G0024013 | ENSPPYP00000006962 | ENSPPYP00000009631 | ATG2B isoform 1. | WIPI1 isoform 2. | 0.964 |
| ATG2B | ENSPPYP00000009167 | ENSPPYP00000006962 | ENSPPYP00000009167 | ATG2B isoform 1. | annotation not available | 0.977 |
| ATG2B | ULK1 | ENSPPYP00000006962 | ENSPPYP00000005848 | ATG2B isoform 1. | Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. | 0.968 |
| ATG2B | ULK2 | ENSPPYP00000006962 | ENSPPYP00000009920 | ATG2B isoform 1. | Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. | 0.970 |
| ATG2B | WDR45B | ENSPPYP00000006962 | ENSPPYP00000009860 | ATG2B isoform 1. | WD repeat domain phosphoinositide-interacting protein 3; Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Binds phosphatidylinositol 3-phosphate (PtdIns3P) forming on membranes of the endoplasmic reticulum upon activation of the upstream ULK1 and PI3 kinases and is recruited at phagophore assembly sites where it regulates the elongation of nascent phagophores downstream of WIPI2. In the cellular response to starvation, may also functi [...] | 0.977 |
| ATG2B | WIPI2 | ENSPPYP00000006962 | ENSPPYP00000019420 | ATG2B isoform 1. | WIPI2 isoform 1. | 0.971 |
| ATG9A | ATG2A | ENSPPYP00000014748 | ENSPPYP00000003576 | Autophagy-related protein 9A; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H (By similarity). | ATG2A isoform 1. | 0.902 |
