| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0002531 | CR201_G0024663 | ENSPPYP00000010106 | ENSPPYP00000013134 | TXNDC2 isoform 4. | TXN2 isoform 1. | 0.539 |
| CR201_G0002531 | NME8 | ENSPPYP00000010106 | ENSPPYP00000019759 | TXNDC2 isoform 4. | NME8 isoform 1. | 0.535 |
| CR201_G0002531 | PRDX1 | ENSPPYP00000010106 | ENSPPYP00000001637 | TXNDC2 isoform 4. | PRDX1 isoform 2. | 0.860 |
| CR201_G0002531 | PRDX2 | ENSPPYP00000010106 | ENSPPYP00000024125 | TXNDC2 isoform 4. | Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2); Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.846 |
| CR201_G0002531 | PRDX3 | ENSPPYP00000010106 | ENSPPYP00000003152 | TXNDC2 isoform 4. | Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.774 |
| CR201_G0002531 | PRDX4 | ENSPPYP00000010106 | ENSPPYP00000022589 | TXNDC2 isoform 4. | PRDX4 isoform 1. | 0.720 |
| CR201_G0002531 | PRDX5 | ENSPPYP00000010106 | ENSPPYP00000003590 | TXNDC2 isoform 4. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.804 |
| CR201_G0002531 | SOD1 | ENSPPYP00000010106 | ENSPPYP00000012676 | TXNDC2 isoform 4. | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. | 0.556 |
| CR201_G0024663 | CR201_G0002531 | ENSPPYP00000013134 | ENSPPYP00000010106 | TXN2 isoform 1. | TXNDC2 isoform 4. | 0.539 |
| CR201_G0024663 | ENSPPYP00000016598 | ENSPPYP00000013134 | ENSPPYP00000016598 | TXN2 isoform 1. | annotation not available | 0.632 |
| CR201_G0024663 | NME8 | ENSPPYP00000013134 | ENSPPYP00000019759 | TXN2 isoform 1. | NME8 isoform 1. | 0.663 |
| CR201_G0024663 | PRDX1 | ENSPPYP00000013134 | ENSPPYP00000001637 | TXN2 isoform 1. | PRDX1 isoform 2. | 0.820 |
| CR201_G0024663 | PRDX2 | ENSPPYP00000013134 | ENSPPYP00000024125 | TXN2 isoform 1. | Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2); Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.754 |
| CR201_G0024663 | PRDX3 | ENSPPYP00000013134 | ENSPPYP00000003152 | TXN2 isoform 1. | Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.983 |
| CR201_G0024663 | PRDX4 | ENSPPYP00000013134 | ENSPPYP00000022589 | TXN2 isoform 1. | PRDX4 isoform 1. | 0.730 |
| CR201_G0024663 | PRDX5 | ENSPPYP00000013134 | ENSPPYP00000003590 | TXN2 isoform 1. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.938 |
| CR201_G0024663 | SOD1 | ENSPPYP00000013134 | ENSPPYP00000012676 | TXN2 isoform 1. | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. | 0.419 |
| CR201_G0024663 | TXN | ENSPPYP00000013134 | ENSPPYP00000021834 | TXN2 isoform 1. | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] | 0.539 |
| ENSPPYP00000016598 | CR201_G0024663 | ENSPPYP00000016598 | ENSPPYP00000013134 | annotation not available | TXN2 isoform 1. | 0.632 |
| ENSPPYP00000016598 | NME8 | ENSPPYP00000016598 | ENSPPYP00000019759 | annotation not available | NME8 isoform 1. | 0.413 |
