| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FBLIM1 | FERMT1 | ENSPPYP00000002131 | ENSPPYP00000011956 | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | 0.942 |
| FBLIM1 | FERMT2 | ENSPPYP00000002131 | ENSPPYP00000006617 | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | FERMT2 isoform 1. | 0.992 |
| FBLIM1 | FERMT3 | ENSPPYP00000002131 | ENSPPYP00000003601 | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | FERMT3 isoform 2. | 0.767 |
| FERMT1 | FBLIM1 | ENSPPYP00000011956 | ENSPPYP00000002131 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | 0.942 |
| FERMT1 | FERMT2 | ENSPPYP00000011956 | ENSPPYP00000006617 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | FERMT2 isoform 1. | 0.792 |
| FERMT1 | FERMT3 | ENSPPYP00000011956 | ENSPPYP00000003601 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | FERMT3 isoform 2. | 0.819 |
| FERMT1 | ITGB2 | ENSPPYP00000011956 | ENSPPYP00000012844 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | Integrin beta. | 0.679 |
| FERMT1 | ITGB3 | ENSPPYP00000011956 | ENSPPYP00000010043 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | Integrin beta. | 0.752 |
| FERMT1 | ITGB5 | ENSPPYP00000011956 | ENSPPYP00000015061 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | Integrin beta; Belongs to the integrin beta chain family. | 0.724 |
| FERMT1 | ITGB7 | ENSPPYP00000011956 | ENSPPYP00000005214 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | Integrin beta; Belongs to the integrin beta chain family. | 0.698 |
| FERMT1 | ITGB8 | ENSPPYP00000011956 | ENSPPYP00000019894 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | Integrin beta; Belongs to the integrin beta chain family. | 0.728 |
| FERMT1 | NCKAP1L | ENSPPYP00000011956 | ENSPPYP00000005254 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | NCK associated protein 1 like. | 0.423 |
| FERMT2 | FBLIM1 | ENSPPYP00000006617 | ENSPPYP00000002131 | FERMT2 isoform 1. | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | 0.992 |
| FERMT2 | FERMT1 | ENSPPYP00000006617 | ENSPPYP00000011956 | FERMT2 isoform 1. | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. | 0.792 |
| FERMT2 | FERMT3 | ENSPPYP00000006617 | ENSPPYP00000003601 | FERMT2 isoform 1. | FERMT3 isoform 2. | 0.800 |
| FERMT2 | ITGB2 | ENSPPYP00000006617 | ENSPPYP00000012844 | FERMT2 isoform 1. | Integrin beta. | 0.622 |
| FERMT2 | ITGB3 | ENSPPYP00000006617 | ENSPPYP00000010043 | FERMT2 isoform 1. | Integrin beta. | 0.766 |
| FERMT2 | ITGB5 | ENSPPYP00000006617 | ENSPPYP00000015061 | FERMT2 isoform 1. | Integrin beta; Belongs to the integrin beta chain family. | 0.743 |
| FERMT2 | ITGB7 | ENSPPYP00000006617 | ENSPPYP00000005214 | FERMT2 isoform 1. | Integrin beta; Belongs to the integrin beta chain family. | 0.643 |
| FERMT2 | ITGB8 | ENSPPYP00000006617 | ENSPPYP00000019894 | FERMT2 isoform 1. | Integrin beta; Belongs to the integrin beta chain family. | 0.698 |
