STIP1 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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[Homology]

Score

STIP1

STIP1 isoform 2. (543 aa)

Predicted Functional Partners:

HSPA4

0.987

HSP90AB1

0.983

AHSA1

0.973

FKBP4

0.963

HSPA6

0.961

AHSA2P

0.954

HSP90AA1

0.951

ENSPPYP00000017062

0.951

PRNP

0.949

PTGES3

0.945

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSA1	ENSPPYP00000017062	ENSPPYP00000006854	ENSPPYP00000017062	AHSA1 isoform 1.	annotation not available	0.922
AHSA1	FKBP4	ENSPPYP00000006854	ENSPPYP00000004732	AHSA1 isoform 1.	Peptidylprolyl isomerase.	0.892
AHSA1	HSP90AA1	ENSPPYP00000006854	ENSPPYP00000006994	AHSA1 isoform 1.	HSP90AA1 isoform 6.	0.922
AHSA1	HSP90AB1	ENSPPYP00000006854	ENSPPYP00000018631	AHSA1 isoform 1.	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.982
AHSA1	HSPA4	ENSPPYP00000006854	ENSPPYP00000017643	AHSA1 isoform 1.	Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.	0.638
AHSA1	HSPA6	ENSPPYP00000006854	ENSPPYP00000000695	AHSA1 isoform 1.	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	0.442
AHSA1	PTGES3	ENSPPYP00000006854	ENSPPYP00000005319	AHSA1 isoform 1.	Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.	0.865
AHSA1	STIP1	ENSPPYP00000006854	ENSPPYP00000003602	AHSA1 isoform 1.	STIP1 isoform 2.	0.973
AHSA2P	ENSPPYP00000017062	ENSPPYP00000013812	ENSPPYP00000017062	AHSA2 isoform 5.	annotation not available	0.612
AHSA2P	FKBP4	ENSPPYP00000013812	ENSPPYP00000004732	AHSA2 isoform 5.	Peptidylprolyl isomerase.	0.789
AHSA2P	HSP90AA1	ENSPPYP00000013812	ENSPPYP00000006994	AHSA2 isoform 5.	HSP90AA1 isoform 6.	0.612
AHSA2P	HSP90AB1	ENSPPYP00000013812	ENSPPYP00000018631	AHSA2 isoform 5.	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.612
AHSA2P	HSPA4	ENSPPYP00000013812	ENSPPYP00000017643	AHSA2 isoform 5.	Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.	0.589
AHSA2P	HSPA6	ENSPPYP00000013812	ENSPPYP00000000695	AHSA2 isoform 5.	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	0.442
AHSA2P	PTGES3	ENSPPYP00000013812	ENSPPYP00000005319	AHSA2 isoform 5.	Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.	0.798
AHSA2P	STIP1	ENSPPYP00000013812	ENSPPYP00000003602	AHSA2 isoform 5.	STIP1 isoform 2.	0.954
ENSPPYP00000017062	AHSA1	ENSPPYP00000017062	ENSPPYP00000006854	annotation not available	AHSA1 isoform 1.	0.922
ENSPPYP00000017062	AHSA2P	ENSPPYP00000017062	ENSPPYP00000013812	annotation not available	AHSA2 isoform 5.	0.612
ENSPPYP00000017062	FKBP4	ENSPPYP00000017062	ENSPPYP00000004732	annotation not available	Peptidylprolyl isomerase.	0.926
ENSPPYP00000017062	HSP90AB1	ENSPPYP00000017062	ENSPPYP00000018631	annotation not available	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.983