| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0046155 | PDZK1 | ENSPPYP00000018221 | ENSPPYP00000001092 | SLC17A4 isoform 3. | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | 0.712 |
| CR201_G0046155 | SLC16A9 | ENSPPYP00000018221 | ENSPPYP00000002813 | SLC17A4 isoform 3. | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | 0.464 |
| CR201_G0046155 | SLC17A1 | ENSPPYP00000018221 | ENSPPYP00000018222 | SLC17A4 isoform 3. | Solute carrier family 17 member 1. | 0.933 |
| CR201_G0046155 | SLC17A2 | ENSPPYP00000018221 | ENSPPYP00000018224 | SLC17A4 isoform 3. | Solute carrier family 17 member 2. | 0.932 |
| CR201_G0046155 | SLC22A6 | ENSPPYP00000018221 | ENSPPYP00000003625 | SLC17A4 isoform 3. | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3- dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxy [...] | 0.740 |
| CR201_G0046155 | SLC22A8 | ENSPPYP00000018221 | ENSPPYP00000003623 | SLC17A4 isoform 3. | Solute carrier family 22 member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | 0.517 |
| PDZK1 | CR201_G0046155 | ENSPPYP00000001092 | ENSPPYP00000018221 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | SLC17A4 isoform 3. | 0.712 |
| PDZK1 | SLC16A9 | ENSPPYP00000001092 | ENSPPYP00000002813 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | 0.487 |
| PDZK1 | SLC17A1 | ENSPPYP00000001092 | ENSPPYP00000018222 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | Solute carrier family 17 member 1. | 0.627 |
| PDZK1 | SLC22A6 | ENSPPYP00000001092 | ENSPPYP00000003625 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3- dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxy [...] | 0.554 |
| PDZK1 | SLC2A9 | ENSPPYP00000001092 | ENSPPYP00000016315 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter, which may play a role in the urate reabsorption by proximal tubules (By similarity). Does not transport glucose, fructose or galactose (By similarity). | 0.476 |
| SLC16A5 | SLC22A6 | ENSPPYP00000009677 | ENSPPYP00000003625 | Solute carrier family 16 member 5. | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3- dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxy [...] | 0.660 |
| SLC16A5 | SLC38A10 | ENSPPYP00000009677 | ENSPPYP00000009800 | Solute carrier family 16 member 5. | Putative sodium-coupled neutral amino acid transporter 10; Putative sodium-dependent amino acid/proton antiporter. Belongs to the amino acid/polyamine transporter 2 family. | 0.868 |
| SLC16A6 | SLC22A6 | ENSPPYP00000009629 | ENSPPYP00000003625 | Solute carrier family 16 member 6. | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3- dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxy [...] | 0.678 |
| SLC16A6 | SLC38A10 | ENSPPYP00000009629 | ENSPPYP00000009800 | Solute carrier family 16 member 6. | Putative sodium-coupled neutral amino acid transporter 10; Putative sodium-dependent amino acid/proton antiporter. Belongs to the amino acid/polyamine transporter 2 family. | 0.671 |
| SLC16A9 | CR201_G0046155 | ENSPPYP00000002813 | ENSPPYP00000018221 | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | SLC17A4 isoform 3. | 0.464 |
| SLC16A9 | PDZK1 | ENSPPYP00000002813 | ENSPPYP00000001092 | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | 0.487 |
| SLC16A9 | SLC17A1 | ENSPPYP00000002813 | ENSPPYP00000018222 | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | Solute carrier family 17 member 1. | 0.487 |
| SLC16A9 | SLC22A6 | ENSPPYP00000002813 | ENSPPYP00000003625 | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3- dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxy [...] | 0.617 |
| SLC16A9 | SLC2A9 | ENSPPYP00000002813 | ENSPPYP00000016315 | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter, which may play a role in the urate reabsorption by proximal tubules (By similarity). Does not transport glucose, fructose or galactose (By similarity). | 0.582 |
