| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMFR | FAF1 | ENSPPYP00000008318 | ENSPPYP00000024718 | AMFR isoform 1. | Fas associated factor 1. | 0.592 |
| AMFR | FAF2 | ENSPPYP00000008318 | ENSPPYP00000017988 | AMFR isoform 1. | Fas associated factor family member 2. | 0.945 |
| AMFR | UBXN1 | ENSPPYP00000008318 | ENSPPYP00000003643 | AMFR isoform 1. | UBXN1 isoform 1. | 0.973 |
| AMFR | UBXN7 | ENSPPYP00000008318 | ENSPPYP00000016149 | AMFR isoform 1. | UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates (By similarity). | 0.597 |
| AMFR | UBXN8 | ENSPPYP00000008318 | ENSPPYP00000020726 | AMFR isoform 1. | UBXN8 isoform 1. | 0.454 |
| AMFR | VCP | ENSPPYP00000008318 | ENSPPYP00000021408 | AMFR isoform 1. | Transitional endoplasmic reticulum ATPase isoform X1. | 0.985 |
| FAF1 | AMFR | ENSPPYP00000024718 | ENSPPYP00000008318 | Fas associated factor 1. | AMFR isoform 1. | 0.592 |
| FAF1 | FAF2 | ENSPPYP00000024718 | ENSPPYP00000017988 | Fas associated factor 1. | Fas associated factor family member 2. | 0.475 |
| FAF1 | NSFL1C | ENSPPYP00000024718 | ENSPPYP00000012121 | Fas associated factor 1. | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | 0.945 |
| FAF1 | UBXN1 | ENSPPYP00000024718 | ENSPPYP00000003643 | Fas associated factor 1. | UBXN1 isoform 1. | 0.969 |
| FAF1 | UBXN2A | ENSPPYP00000024718 | ENSPPYP00000014077 | Fas associated factor 1. | UBXN2A isoform 2. | 0.490 |
| FAF1 | UBXN6 | ENSPPYP00000024718 | ENSPPYP00000010548 | Fas associated factor 1. | UBXN6 isoform 3. | 0.954 |
| FAF1 | UBXN7 | ENSPPYP00000024718 | ENSPPYP00000016149 | Fas associated factor 1. | UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates (By similarity). | 0.970 |
| FAF1 | VCP | ENSPPYP00000024718 | ENSPPYP00000021408 | Fas associated factor 1. | Transitional endoplasmic reticulum ATPase isoform X1. | 0.964 |
| FAF2 | AMFR | ENSPPYP00000017988 | ENSPPYP00000008318 | Fas associated factor family member 2. | AMFR isoform 1. | 0.945 |
| FAF2 | FAF1 | ENSPPYP00000017988 | ENSPPYP00000024718 | Fas associated factor family member 2. | Fas associated factor 1. | 0.475 |
| FAF2 | NSFL1C | ENSPPYP00000017988 | ENSPPYP00000012121 | Fas associated factor family member 2. | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | 0.510 |
| FAF2 | UBXN1 | ENSPPYP00000017988 | ENSPPYP00000003643 | Fas associated factor family member 2. | UBXN1 isoform 1. | 0.959 |
| FAF2 | UBXN2A | ENSPPYP00000017988 | ENSPPYP00000014077 | Fas associated factor family member 2. | UBXN2A isoform 2. | 0.546 |
| FAF2 | UBXN4 | ENSPPYP00000017988 | ENSPPYP00000014304 | Fas associated factor family member 2. | UBX domain-containing protein 4; Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD. | 0.439 |
