STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTNND1CTNND1 isoform 19. (968 aa)    
Predicted Functional Partners:
CTNNB1
CTNNB1 isoform 2.
   
 0.998
CDH5
CDH5 isoform 2; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.990
CDH2
Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic s [...]
    
 0.988
ZBTB33
Zinc finger and BTB domain containing 33.
    
 
 0.986
CTNNA1
CTNNA1 isoform 1.
   
 0.983
CDH17
CDH17 isoform 1.
    
 0.947
CDH3
CDH3 isoform 2; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.927
EGFR
Receptor protein-tyrosine kinase.
    
 
 0.927
CR201_G0027422
VAV2 isoform 3.
    
 0.867
CDH4
CDH4 isoform 1; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.821
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.