| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CELF1 | CR201_G0050254 | ENSPPYP00000003787 | ENSPPYP00000020986 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | RALYL isoform 7. | 0.712 |
| CELF1 | ENSPPYP00000001461 | ENSPPYP00000003787 | ENSPPYP00000001461 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | annotation not available | 0.811 |
| CELF1 | ENSPPYP00000018739 | ENSPPYP00000003787 | ENSPPYP00000018739 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | annotation not available | 0.648 |
| CELF1 | ENSPPYP00000019655 | ENSPPYP00000003787 | ENSPPYP00000019655 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | annotation not available | 0.811 |
| CELF1 | HNRNPC | ENSPPYP00000003787 | ENSPPYP00000006361 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | Heterogeneous nuclear ribonucleoprotein C; Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilit [...] | 0.950 |
| CELF1 | HNRNPH1 | ENSPPYP00000003787 | ENSPPYP00000018037 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | HNRNPH1 isoform 9. | 0.662 |
| CELF1 | MBNL1 | ENSPPYP00000003787 | ENSPPYP00000015898 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | Muscleblind like splicing regulator 1. | 0.884 |
| CELF1 | MBNL3 | ENSPPYP00000003787 | ENSPPYP00000023203 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | Muscleblind like splicing regulator 3. | 0.699 |
| CELF1 | NOTCH1 | ENSPPYP00000003787 | ENSPPYP00000022176 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | NOTCH1 isoform 1. | 0.748 |
| CELF1 | RALY | ENSPPYP00000003787 | ENSPPYP00000024392 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | RALY heterogeneous nuclear ribonucleoprotein. | 0.922 |
| CR201_G0050254 | CELF1 | ENSPPYP00000020986 | ENSPPYP00000003787 | RALYL isoform 7. | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | 0.712 |
| CR201_G0050254 | ENSPPYP00000001461 | ENSPPYP00000020986 | ENSPPYP00000001461 | RALYL isoform 7. | annotation not available | 0.787 |
| CR201_G0050254 | ENSPPYP00000019655 | ENSPPYP00000020986 | ENSPPYP00000019655 | RALYL isoform 7. | annotation not available | 0.787 |
| CR201_G0050254 | HNRNPC | ENSPPYP00000020986 | ENSPPYP00000006361 | RALYL isoform 7. | Heterogeneous nuclear ribonucleoprotein C; Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilit [...] | 0.931 |
| CR201_G0050254 | HNRNPH1 | ENSPPYP00000020986 | ENSPPYP00000018037 | RALYL isoform 7. | HNRNPH1 isoform 9. | 0.439 |
| CR201_G0050254 | RALY | ENSPPYP00000020986 | ENSPPYP00000024392 | RALYL isoform 7. | RALY heterogeneous nuclear ribonucleoprotein. | 0.915 |
| ENSPPYP00000001461 | CELF1 | ENSPPYP00000001461 | ENSPPYP00000003787 | annotation not available | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | 0.811 |
| ENSPPYP00000001461 | CR201_G0050254 | ENSPPYP00000001461 | ENSPPYP00000020986 | annotation not available | RALYL isoform 7. | 0.787 |
| ENSPPYP00000001461 | HNRNPH1 | ENSPPYP00000001461 | ENSPPYP00000018037 | annotation not available | HNRNPH1 isoform 9. | 0.509 |
| ENSPPYP00000001461 | RALY | ENSPPYP00000001461 | ENSPPYP00000024392 | annotation not available | RALY heterogeneous nuclear ribonucleoprotein. | 0.843 |
