F2 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F13A1	F13B	ENSPPYP00000018120	ENSPPYP00000024425	F13A1 isoform 1.	F13B isoform 1.	0.999
F13A1	F2	ENSPPYP00000018120	ENSPPYP00000003807	F13A1 isoform 1.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	0.986
F13A1	FGA	ENSPPYP00000018120	ENSPPYP00000016920	F13A1 isoform 1.	FGA isoform 1.	0.788
F13A1	FGB	ENSPPYP00000018120	ENSPPYP00000016918	F13A1 isoform 1.	FGB isoform 1.	0.515
F13A1	FGG	ENSPPYP00000018120	ENSPPYP00000016921	F13A1 isoform 1.	FGG isoform 2.	0.563
F13A1	SERPINC1	ENSPPYP00000018120	ENSPPYP00000000566	F13A1 isoform 1.	Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity).	0.556
F13A1	SERPIND1	ENSPPYP00000018120	ENSPPYP00000013411	F13A1 isoform 1.	SERPIND1 isoform 1; Belongs to the serpin family.	0.551
F13B	F13A1	ENSPPYP00000024425	ENSPPYP00000018120	F13B isoform 1.	F13A1 isoform 1.	0.999
F13B	F2	ENSPPYP00000024425	ENSPPYP00000003807	F13B isoform 1.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	0.995
F13B	F5	ENSPPYP00000024425	ENSPPYP00000000617	F13B isoform 1.	F5 isoform 3; Belongs to the multicopper oxidase family.	0.777
F13B	FGA	ENSPPYP00000024425	ENSPPYP00000016920	F13B isoform 1.	FGA isoform 1.	0.875
F13B	FGB	ENSPPYP00000024425	ENSPPYP00000016918	F13B isoform 1.	FGB isoform 1.	0.786
F13B	FGG	ENSPPYP00000024425	ENSPPYP00000016921	F13B isoform 1.	FGG isoform 2.	0.878
F13B	SERPINC1	ENSPPYP00000024425	ENSPPYP00000000566	F13B isoform 1.	Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity).	0.823
F13B	SERPIND1	ENSPPYP00000024425	ENSPPYP00000013411	F13B isoform 1.	SERPIND1 isoform 1; Belongs to the serpin family.	0.921
F2	F13A1	ENSPPYP00000003807	ENSPPYP00000018120	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F13A1 isoform 1.	0.986
F2	F13B	ENSPPYP00000003807	ENSPPYP00000024425	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F13B isoform 1.	0.995
F2	F2R	ENSPPYP00000003807	ENSPPYP00000017406	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F2R isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.997
F2	F2RL3	ENSPPYP00000003807	ENSPPYP00000010868	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F2RL3 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.995
F2	F5	ENSPPYP00000003807	ENSPPYP00000000617	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F5 isoform 3; Belongs to the multicopper oxidase family.	0.984