| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EP300 | ID1 | ENSPPYP00000013236 | ENSPPYP00000012162 | EP300 isoform 1. | Inhibitor of DNA binding 1, HLH protein. | 0.443 |
| EP300 | KAT2B | ENSPPYP00000013236 | ENSPPYP00000015742 | EP300 isoform 1. | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | 0.999 |
| EP300 | MEF2A | ENSPPYP00000013236 | ENSPPYP00000007730 | EP300 isoform 1. | Myocyte-specific enhancer factor 2A; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylate [...] | 0.843 |
| EP300 | MEF2C | ENSPPYP00000013236 | ENSPPYP00000017465 | EP300 isoform 1. | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | 0.792 |
| EP300 | MYOD1 | ENSPPYP00000013236 | ENSPPYP00000003961 | EP300 isoform 1. | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. | 0.944 |
| EP300 | TBP | ENSPPYP00000013236 | ENSPPYP00000019257 | EP300 isoform 1. | TBP isoform 3. | 0.600 |
| EP300 | TBPL2 | ENSPPYP00000013236 | ENSPPYP00000006636 | EP300 isoform 1. | TATA-box binding protein like 2. | 0.553 |
| EP300 | TCF3 | ENSPPYP00000013236 | ENSPPYP00000010467 | EP300 isoform 1. | TCF3 isoform 5. | 0.856 |
| FBXO32 | MYOD1 | ENSPPYP00000021159 | ENSPPYP00000003961 | FBXO32 isoform 2. | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. | 0.894 |
| ID1 | EP300 | ENSPPYP00000012162 | ENSPPYP00000013236 | Inhibitor of DNA binding 1, HLH protein. | EP300 isoform 1. | 0.443 |
| ID1 | MYOD1 | ENSPPYP00000012162 | ENSPPYP00000003961 | Inhibitor of DNA binding 1, HLH protein. | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. | 0.931 |
| ID1 | TCF3 | ENSPPYP00000012162 | ENSPPYP00000010467 | Inhibitor of DNA binding 1, HLH protein. | TCF3 isoform 5. | 0.952 |
| KAT2B | EP300 | ENSPPYP00000015742 | ENSPPYP00000013236 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | EP300 isoform 1. | 0.999 |
| KAT2B | MYOD1 | ENSPPYP00000015742 | ENSPPYP00000003961 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. | 0.932 |
| KAT2B | TBP | ENSPPYP00000015742 | ENSPPYP00000019257 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | TBP isoform 3. | 0.888 |
| KAT2B | TBPL1 | ENSPPYP00000015742 | ENSPPYP00000019061 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | TATA box-binding protein-like protein 1; Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box (By similarity). | 0.649 |
| KAT2B | TBPL2 | ENSPPYP00000015742 | ENSPPYP00000006636 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | TATA-box binding protein like 2. | 0.864 |
| KAT2B | TCF3 | ENSPPYP00000015742 | ENSPPYP00000010467 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | TCF3 isoform 5. | 0.571 |
| MEF2A | EP300 | ENSPPYP00000007730 | ENSPPYP00000013236 | Myocyte-specific enhancer factor 2A; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylate [...] | EP300 isoform 1. | 0.843 |
| MEF2A | MEF2C | ENSPPYP00000007730 | ENSPPYP00000017465 | Myocyte-specific enhancer factor 2A; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylate [...] | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | 0.997 |
