SPON1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	GNG4	ENSPPYP00000012629	ENSPPYP00000000094	APP isoform 3.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.609
APP	SPON1	ENSPPYP00000012629	ENSPPYP00000003981	APP isoform 3.	SPON1 isoform 1.	0.502
B3GLCT	POFUT2	ENSPPYP00000005988	ENSPPYP00000012854	Beta 3-glucosyltransferase.	Protein O-fucosyltransferase 2.	0.688
B3GLCT	SPON1	ENSPPYP00000005988	ENSPPYP00000003981	Beta 3-glucosyltransferase.	SPON1 isoform 1.	0.753
CPNE8	GNG4	ENSPPYP00000005034	ENSPPYP00000000094	CPNE8 isoform 2.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.568
CPNE8	RCAN2	ENSPPYP00000005034	ENSPPYP00000018648	CPNE8 isoform 2.	Calcipressin-2; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).	0.568
CPNE8	SPON1	ENSPPYP00000005034	ENSPPYP00000003981	CPNE8 isoform 2.	SPON1 isoform 1.	0.568
CPNE8	VSTM2L	ENSPPYP00000005034	ENSPPYP00000012275	CPNE8 isoform 2.	VSTM2L isoform 1.	0.530
CPNE8	ZNF385B	ENSPPYP00000005034	ENSPPYP00000014505	CPNE8 isoform 2.	Zinc finger protein 385B.	0.453
CSTF3	SPON1	ENSPPYP00000003876	ENSPPYP00000003981	Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs.	SPON1 isoform 1.	0.492
GID8	SPON1	ENSPPYP00000012537	ENSPPYP00000003981	GID8 isoform 1.	SPON1 isoform 1.	0.492
GNG4	APP	ENSPPYP00000000094	ENSPPYP00000012629	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	APP isoform 3.	0.609
GNG4	CPNE8	ENSPPYP00000000094	ENSPPYP00000005034	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	CPNE8 isoform 2.	0.568
GNG4	RCAN2	ENSPPYP00000000094	ENSPPYP00000018648	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Calcipressin-2; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).	0.634
GNG4	SPON1	ENSPPYP00000000094	ENSPPYP00000003981	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	SPON1 isoform 1.	0.635
GNG4	VSTM2L	ENSPPYP00000000094	ENSPPYP00000012275	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	VSTM2L isoform 1.	0.641
GNG4	ZNF385B	ENSPPYP00000000094	ENSPPYP00000014505	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Zinc finger protein 385B.	0.504
POFUT2	B3GLCT	ENSPPYP00000012854	ENSPPYP00000005988	Protein O-fucosyltransferase 2.	Beta 3-glucosyltransferase.	0.688
POFUT2	SPON1	ENSPPYP00000012854	ENSPPYP00000003981	Protein O-fucosyltransferase 2.	SPON1 isoform 1.	0.748
RCAN2	CPNE8	ENSPPYP00000018648	ENSPPYP00000005034	Calcipressin-2; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).	CPNE8 isoform 2.	0.568