NRIP3 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NRIP3

Nuclear receptor-interacting protein 3. (240 aa)

Predicted Functional Partners:

DDI1

0.765

RAD23A

0.519

RAD23B

0.519

TBC1D30

0.480

PSMD4

0.442

PSMD2

0.441

DDI2

0.404

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDI1	NRIP3	ENSPPYP00000004371	ENSPPYP00000004014	DNA damage inducible 1 homolog 1.	Nuclear receptor-interacting protein 3.	0.765
DDI1	PSMD2	ENSPPYP00000004371	ENSPPYP00000016052	DNA damage inducible 1 homolog 1.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.	0.444
DDI1	PSMD4	ENSPPYP00000004371	ENSPPYP00000024378	DNA damage inducible 1 homolog 1.	PSMD4 isoform 1.	0.584
DDI1	RAD23A	ENSPPYP00000004371	ENSPPYP00000010781	DNA damage inducible 1 homolog 1.	RAD23A isoform 1.	0.472
DDI2	NRIP3	ENSPPYP00000002135	ENSPPYP00000004014	DNA damage inducible 1 homolog 2.	Nuclear receptor-interacting protein 3.	0.404
DDI2	PSMD2	ENSPPYP00000002135	ENSPPYP00000016052	DNA damage inducible 1 homolog 2.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.	0.509
DDI2	PSMD4	ENSPPYP00000002135	ENSPPYP00000024378	DNA damage inducible 1 homolog 2.	PSMD4 isoform 1.	0.499
DDI2	RAD23A	ENSPPYP00000002135	ENSPPYP00000010781	DNA damage inducible 1 homolog 2.	RAD23A isoform 1.	0.579
DDI2	RAD23B	ENSPPYP00000002135	ENSPPYP00000021817	DNA damage inducible 1 homolog 2.	RAD23 homolog B, nucleotide excision repair protein.	0.579
NRIP3	DDI1	ENSPPYP00000004014	ENSPPYP00000004371	Nuclear receptor-interacting protein 3.	DNA damage inducible 1 homolog 1.	0.765
NRIP3	DDI2	ENSPPYP00000004014	ENSPPYP00000002135	Nuclear receptor-interacting protein 3.	DNA damage inducible 1 homolog 2.	0.404
NRIP3	PSMD2	ENSPPYP00000004014	ENSPPYP00000016052	Nuclear receptor-interacting protein 3.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.	0.441
NRIP3	PSMD4	ENSPPYP00000004014	ENSPPYP00000024378	Nuclear receptor-interacting protein 3.	PSMD4 isoform 1.	0.442
NRIP3	RAD23A	ENSPPYP00000004014	ENSPPYP00000010781	Nuclear receptor-interacting protein 3.	RAD23A isoform 1.	0.519
NRIP3	RAD23B	ENSPPYP00000004014	ENSPPYP00000021817	Nuclear receptor-interacting protein 3.	RAD23 homolog B, nucleotide excision repair protein.	0.519
NRIP3	TBC1D30	ENSPPYP00000004014	ENSPPYP00000005390	Nuclear receptor-interacting protein 3.	TBC1 domain family member 30.	0.480
PSMD2	DDI1	ENSPPYP00000016052	ENSPPYP00000004371	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.	DNA damage inducible 1 homolog 1.	0.444
PSMD2	DDI2	ENSPPYP00000016052	ENSPPYP00000002135	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.	DNA damage inducible 1 homolog 2.	0.509
PSMD2	NRIP3	ENSPPYP00000016052	ENSPPYP00000004014	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.	Nuclear receptor-interacting protein 3.	0.441
PSMD2	PSMD4	ENSPPYP00000016052	ENSPPYP00000024378	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.	PSMD4 isoform 1.	0.995