Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM22TRIM22 isoform 3. (498 aa)    
Predicted Functional Partners:
TRAT1
T cell receptor associated transmembrane adaptor 1.
      
 0.718
PNRC1
PNRC1 isoform 1.
      
 0.672
FKBP1B
Peptidylprolyl isomerase.
    
 
 0.659
LACC1
T0057068 isoform 1.
    
 
 0.618
LOC100458762
CMP/dCMP-type deaminase domain-containing protein.
   
  
 0.616
LRBA
LRBA isoform 2.
    
 
 0.605
APOBEC3F
DNA dC->dU-editing enzyme APOBEC-3F isoform X1.
   
  
 0.576
NOD2
NOD2 isoform 4.
   
 0.573
NFKBIA
NFKBIA isoform 1.
    
 0.564
GUCY2C
Guanylate cyclase.
    
 
 0.554
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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