| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LAMTOR1 | LAMTOR2 | ENSPPYP00000004168 | ENSPPYP00000000848 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | 0.999 |
| LAMTOR1 | LAMTOR3 | ENSPPYP00000004168 | ENSPPYP00000016698 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | Ragulator complex protein LAMTOR3; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP k [...] | 0.999 |
| LAMTOR1 | LAMTOR4 | ENSPPYP00000004168 | ENSPPYP00000019501 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | Ragulator complex protein LAMTOR4, N-terminally processed; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity). | 0.999 |
| LAMTOR1 | LAMTOR5 | ENSPPYP00000004168 | ENSPPYP00000001218 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | LAMTOR5 isoform 1. | 0.999 |
| LAMTOR1 | RPTOR | ENSPPYP00000004168 | ENSPPYP00000024617 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | RPTOR isoform 4. | 0.998 |
| LAMTOR1 | RRAGA | ENSPPYP00000004168 | ENSPPYP00000021503 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | Ras related GTP binding A. | 0.999 |
| LAMTOR1 | RRAGB | ENSPPYP00000004168 | ENSPPYP00000022833 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | Ras related GTP binding B. | 0.998 |
| LAMTOR1 | RRAGC | ENSPPYP00000004168 | ENSPPYP00000001752 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | RRAGC isoform 1. | 0.999 |
| LAMTOR1 | RRAGD | ENSPPYP00000004168 | ENSPPYP00000018853 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | RRAGD isoform 1. | 0.998 |
| LAMTOR1 | SLC38A9 | ENSPPYP00000004168 | ENSPPYP00000017287 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | SLC38A9 isoform 14. | 0.999 |
| LAMTOR2 | LAMTOR1 | ENSPPYP00000000848 | ENSPPYP00000004168 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] | 0.999 |
| LAMTOR2 | LAMTOR3 | ENSPPYP00000000848 | ENSPPYP00000016698 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | Ragulator complex protein LAMTOR3; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP k [...] | 0.999 |
| LAMTOR2 | LAMTOR4 | ENSPPYP00000000848 | ENSPPYP00000019501 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | Ragulator complex protein LAMTOR4, N-terminally processed; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity). | 0.999 |
| LAMTOR2 | LAMTOR5 | ENSPPYP00000000848 | ENSPPYP00000001218 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | LAMTOR5 isoform 1. | 0.999 |
| LAMTOR2 | RPTOR | ENSPPYP00000000848 | ENSPPYP00000024617 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | RPTOR isoform 4. | 0.971 |
| LAMTOR2 | RRAGA | ENSPPYP00000000848 | ENSPPYP00000021503 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | Ras related GTP binding A. | 0.999 |
| LAMTOR2 | RRAGB | ENSPPYP00000000848 | ENSPPYP00000022833 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | Ras related GTP binding B. | 0.998 |
| LAMTOR2 | RRAGC | ENSPPYP00000000848 | ENSPPYP00000001752 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | RRAGC isoform 1. | 0.999 |
| LAMTOR2 | RRAGD | ENSPPYP00000000848 | ENSPPYP00000018853 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | RRAGD isoform 1. | 0.963 |
| LAMTOR2 | SLC38A9 | ENSPPYP00000000848 | ENSPPYP00000017287 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. | SLC38A9 isoform 14. | 0.999 |