| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL | CR201_G0037390 | ENSPPYP00000004540 | ENSPPYP00000010903 | Cbl proto-oncogene. | PIK3R2 isoform 1. | 0.985 |
| CBL | INPP5D | ENSPPYP00000004540 | ENSPPYP00000014855 | Cbl proto-oncogene. | INPP5D isoform 3. | 0.754 |
| CBL | INPPL1 | ENSPPYP00000004540 | ENSPPYP00000004172 | Cbl proto-oncogene. | INPPL1 isoform 2. | 0.944 |
| CBL | PIK3CA | ENSPPYP00000004540 | ENSPPYP00000023529 | Cbl proto-oncogene. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.967 |
| CBL | PIK3CB | ENSPPYP00000004540 | ENSPPYP00000015827 | Cbl proto-oncogene. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.968 |
| CBL | PIK3CD | ENSPPYP00000004540 | ENSPPYP00000002213 | Cbl proto-oncogene. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.900 |
| CBL | PIK3R1 | ENSPPYP00000004540 | ENSPPYP00000017341 | Cbl proto-oncogene. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.986 |
| CBL | PIK3R3 | ENSPPYP00000004540 | ENSPPYP00000001627 | Cbl proto-oncogene. | T0148502 isoform 1. | 0.898 |
| CBL | SHC1 | ENSPPYP00000004540 | ENSPPYP00000000893 | Cbl proto-oncogene. | SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity). | 0.958 |
| CR201_G0037390 | CBL | ENSPPYP00000010903 | ENSPPYP00000004540 | PIK3R2 isoform 1. | Cbl proto-oncogene. | 0.985 |
| CR201_G0037390 | INPP4A | ENSPPYP00000010903 | ENSPPYP00000013473 | PIK3R2 isoform 1. | INPP4A isoform 2. | 0.903 |
| CR201_G0037390 | INPP5D | ENSPPYP00000010903 | ENSPPYP00000014855 | PIK3R2 isoform 1. | INPP5D isoform 3. | 0.943 |
| CR201_G0037390 | INPPL1 | ENSPPYP00000010903 | ENSPPYP00000004172 | PIK3R2 isoform 1. | INPPL1 isoform 2. | 0.954 |
| CR201_G0037390 | PIK3CA | ENSPPYP00000010903 | ENSPPYP00000023529 | PIK3R2 isoform 1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.999 |
| CR201_G0037390 | PIK3CB | ENSPPYP00000010903 | ENSPPYP00000015827 | PIK3R2 isoform 1. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.999 |
| CR201_G0037390 | PIK3CD | ENSPPYP00000010903 | ENSPPYP00000002213 | PIK3R2 isoform 1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.997 |
| CR201_G0037390 | PIK3R1 | ENSPPYP00000010903 | ENSPPYP00000017341 | PIK3R2 isoform 1. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.997 |
| CR201_G0037390 | PIK3R3 | ENSPPYP00000010903 | ENSPPYP00000001627 | PIK3R2 isoform 1. | T0148502 isoform 1. | 0.996 |
| CR201_G0037390 | SHC1 | ENSPPYP00000010903 | ENSPPYP00000000893 | PIK3R2 isoform 1. | SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity). | 0.605 |
| INPP4A | CR201_G0037390 | ENSPPYP00000013473 | ENSPPYP00000010903 | INPP4A isoform 2. | PIK3R2 isoform 1. | 0.903 |
