Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DNAJB13DNAJB13 isoform 2. (278 aa)    
Predicted Functional Partners:
HSPA4
Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.
 
 0.931
RSPH4A
Radial spoke head component 4A.
   
 0.890
HSPH1
Heat shock protein 105 kDa; Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
 
 0.866
NME5
NME/NM23 family member 5; Belongs to the NDK family.
    
 0.862
STIP1
STIP1 isoform 2.
   
 0.851
RSPH9
RSPH9 isoform 2.
   
 
 0.844
MAPKAPK5
MAPKAPK5 isoform 3.
    
  0.812
CFAP43
CFAP43 isoform 1.
   
 
 0.809
EFHB
EFHB isoform 1.
   
   0.802
CFAP58
CFAP58 isoform 1.
   
 
 0.800
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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