Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RAB30RAB30, member RAS oncogene family. (203 aa)    
Predicted Functional Partners:
COG4
Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.
    
 0.898
COG5
COG5 isoform 5.
     
 0.857
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.854
COG2
COG2 isoform 1.
     
 0.845
COG8
Conserved oligomeric Golgi complex subunit 8.
     
 0.812
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
     
 0.807
COG1
COG1 isoform 2.
     
 0.775
AVL9
Late secretory pathway protein AVL9 homolog; Functions in cell migration; Belongs to the AVL9 family.
      
 0.728
COG7
COG7 isoform 1.
     
 0.724
COG3
COG3 isoform 1.
     
 0.720
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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