| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAPN1 | CAPN2 | ENSPPYP00000003556 | ENSPPYP00000000188 | Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | CAPN2 isoform 2; Belongs to the peptidase C2 family. | 0.986 |
| CAPN1 | CASP3 | ENSPPYP00000003556 | ENSPPYP00000017020 | Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | CASP3 isoform 1; Belongs to the peptidase C14A family. | 0.493 |
| CAPN1 | CR201_G0025521 | ENSPPYP00000003556 | ENSPPYP00000004372 | Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | CASP12 isoform 3; Belongs to the peptidase C14A family. | 0.915 |
| CAPN2 | CAPN1 | ENSPPYP00000000188 | ENSPPYP00000003556 | CAPN2 isoform 2; Belongs to the peptidase C2 family. | Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | 0.986 |
| CAPN2 | CASP3 | ENSPPYP00000000188 | ENSPPYP00000017020 | CAPN2 isoform 2; Belongs to the peptidase C2 family. | CASP3 isoform 1; Belongs to the peptidase C14A family. | 0.403 |
| CAPN2 | CR201_G0025521 | ENSPPYP00000000188 | ENSPPYP00000004372 | CAPN2 isoform 2; Belongs to the peptidase C2 family. | CASP12 isoform 3; Belongs to the peptidase C14A family. | 0.912 |
| CASP1 | CASP3 | ENSPPYP00000004375 | ENSPPYP00000017020 | CASP1 isoform 4; Belongs to the peptidase C14A family. | CASP3 isoform 1; Belongs to the peptidase C14A family. | 0.928 |
| CASP1 | CASP7 | ENSPPYP00000004375 | ENSPPYP00000003106 | CASP1 isoform 4; Belongs to the peptidase C14A family. | CASP7 isoform 4; Belongs to the peptidase C14A family. | 0.920 |
| CASP1 | CR201_G0025521 | ENSPPYP00000004375 | ENSPPYP00000004372 | CASP1 isoform 4; Belongs to the peptidase C14A family. | CASP12 isoform 3; Belongs to the peptidase C14A family. | 0.900 |
| CASP1 | CR201_G0050806 | ENSPPYP00000004375 | ENSPPYP00000023911 | CASP1 isoform 4; Belongs to the peptidase C14A family. | GSDMD isoform 17. | 0.889 |
| CASP1 | IL1B | ENSPPYP00000004375 | ENSPPYP00000013573 | CASP1 isoform 4; Belongs to the peptidase C14A family. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.996 |
| CASP1 | NLRC4 | ENSPPYP00000004375 | ENSPPYP00000013968 | CASP1 isoform 4; Belongs to the peptidase C14A family. | NLRC4 isoform 1. | 0.996 |
| CASP1 | PYCARD | ENSPPYP00000004375 | ENSPPYP00000008260 | CASP1 isoform 4; Belongs to the peptidase C14A family. | PYD and CARD domain containing. | 0.999 |
| CASP3 | CAPN1 | ENSPPYP00000017020 | ENSPPYP00000003556 | CASP3 isoform 1; Belongs to the peptidase C14A family. | Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | 0.493 |
| CASP3 | CAPN2 | ENSPPYP00000017020 | ENSPPYP00000000188 | CASP3 isoform 1; Belongs to the peptidase C14A family. | CAPN2 isoform 2; Belongs to the peptidase C2 family. | 0.403 |
| CASP3 | CASP1 | ENSPPYP00000017020 | ENSPPYP00000004375 | CASP3 isoform 1; Belongs to the peptidase C14A family. | CASP1 isoform 4; Belongs to the peptidase C14A family. | 0.928 |
| CASP3 | CASP7 | ENSPPYP00000017020 | ENSPPYP00000003106 | CASP3 isoform 1; Belongs to the peptidase C14A family. | CASP7 isoform 4; Belongs to the peptidase C14A family. | 0.969 |
| CASP3 | CR201_G0025521 | ENSPPYP00000017020 | ENSPPYP00000004372 | CASP3 isoform 1; Belongs to the peptidase C14A family. | CASP12 isoform 3; Belongs to the peptidase C14A family. | 0.926 |
| CASP3 | CR201_G0050806 | ENSPPYP00000017020 | ENSPPYP00000023911 | CASP3 isoform 1; Belongs to the peptidase C14A family. | GSDMD isoform 17. | 0.723 |
| CASP3 | IL1B | ENSPPYP00000017020 | ENSPPYP00000013573 | CASP3 isoform 1; Belongs to the peptidase C14A family. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.721 |
