Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CRYAB | HSP90AB1 | ENSPPYP00000004431 | ENSPPYP00000018631 | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.478 |
| CRYAB | HSPA4 | ENSPPYP00000004431 | ENSPPYP00000017643 | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.448 |
| CRYAB | HSPB2 | ENSPPYP00000004431 | ENSPPYP00000004432 | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | HSPB2-C11orf52 isoform 2; Belongs to the small heat shock protein (HSP20) family. | 0.851 |
| CRYAB | MAPKAPK2 | ENSPPYP00000004431 | ENSPPYP00000000301 | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. | 0.469 |
| CRYAB | MAPKAPK5 | ENSPPYP00000004431 | ENSPPYP00000005668 | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | MAPKAPK5 isoform 3. | 0.442 |
| CYCS | HSP90AB1 | ENSPPYP00000019862 | ENSPPYP00000018631 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.558 |
| CYCS | HSPA4 | ENSPPYP00000019862 | ENSPPYP00000017643 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.688 |
| CYCS | HSPB2 | ENSPPYP00000019862 | ENSPPYP00000004432 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | HSPB2-C11orf52 isoform 2; Belongs to the small heat shock protein (HSP20) family. | 0.823 |
| CYCS | HSPB3 | ENSPPYP00000019862 | ENSPPYP00000017276 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family. | 0.823 |
| HSP90AB1 | CRYAB | ENSPPYP00000018631 | ENSPPYP00000004431 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | 0.478 |
| HSP90AB1 | CYCS | ENSPPYP00000018631 | ENSPPYP00000019862 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.558 |
| HSP90AB1 | HSPA4 | ENSPPYP00000018631 | ENSPPYP00000017643 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.986 |
| HSP90AB1 | HSPB2 | ENSPPYP00000018631 | ENSPPYP00000004432 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | HSPB2-C11orf52 isoform 2; Belongs to the small heat shock protein (HSP20) family. | 0.753 |
| HSP90AB1 | HSPB3 | ENSPPYP00000018631 | ENSPPYP00000017276 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family. | 0.751 |
| HSP90AB1 | MAPK14 | ENSPPYP00000018631 | ENSPPYP00000018500 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | Mitogen-activated protein kinase. | 0.450 |
| HSPA4 | CRYAB | ENSPPYP00000017643 | ENSPPYP00000004431 | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | 0.448 |
| HSPA4 | CYCS | ENSPPYP00000017643 | ENSPPYP00000019862 | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.688 |
| HSPA4 | HSP90AB1 | ENSPPYP00000017643 | ENSPPYP00000018631 | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.986 |
| HSPA4 | HSPB2 | ENSPPYP00000017643 | ENSPPYP00000004432 | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | HSPB2-C11orf52 isoform 2; Belongs to the small heat shock protein (HSP20) family. | 0.852 |
| HSPA4 | HSPB3 | ENSPPYP00000017643 | ENSPPYP00000017276 | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family. | 0.851 |
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