Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
HSPB2HSPB2-C11orf52 isoform 2; Belongs to the small heat shock protein (HSP20) family. (182 aa)    
Predicted Functional Partners:
MAPK14
Mitogen-activated protein kinase.
    
 0.955
MAPK12
Mitogen-activated protein kinase.
    
 0.937
MAPK13
Mitogen-activated protein kinase.
    
 0.937
CRYAB
Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
   
 
 0.894
HSPB3
Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family.
  
 
0.885
MYOZ2
Myozenin-2; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis (By similarity).
   
 
 0.857
SGCG
SGCG isoform 1.
   
  
 0.846
HSPB7
HSPB7 isoform 4; Belongs to the small heat shock protein (HSP20) family.
  
  
0.828
HSPA4
Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.
   
 0.739
MAPKAPK2
MAPK activated protein kinase 2; Belongs to the protein kinase superfamily.
    
 0.659
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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