Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NNMTNicotinamide N-methyltransferase. (264 aa)    
Predicted Functional Partners:
NAMPT
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.935
AOX1
AOX1 isoform 2.
   
 
 0.925
SIRT1
SIRT1 isoform 1.
     
 0.916
BST1
BST1 isoform 4.
     
 0.915
SARM1
Sterile alpha and TIR motif containing 1.
     
 0.912
CD38
CD38 isoform 1.
     
 0.911
SIRT7
SIRT7 isoform 2.
     
 0.910
PNP
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
     
 0.908
SIRT6
SIRT6 isoform 1.
     
 0.908
SIRT3
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
     
 0.908
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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