Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MPZL3Myelin protein zero like 3. (235 aa)    
Predicted Functional Partners:
FLOT2
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
   0.796
MEGF11
MEGF11 isoform 1.
      
 0.722
RHBDF1
Rhomboid 5 homolog 1.
      
 0.722
TMEM79
TMEM79 isoform 2.
    
   0.711
CR201_G0023224
MYO7A isoform 2.
      
 0.665
IGF2BP2
Insulin-like growth factor 2 mRNA-binding protein 2; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform- specific. Binds to beta-actin/ACTB and MYC transcripts (By similarity). [...]
      
 0.665
PHACTR1
Phosphatase and actin regulator.
      
 0.655
WSCD2
WSC domain containing 2.
      
 0.654
CR201_G0049470
Receptor expression-enhancing protein.
      
 0.653
FLOT1
Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
    
   0.635
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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