| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABL1 | CBL | ENSPPYP00000022265 | ENSPPYP00000004540 | Tyrosine-protein kinase. | Cbl proto-oncogene. | 0.993 |
| ABL1 | CRK | ENSPPYP00000022265 | ENSPPYP00000008754 | Tyrosine-protein kinase. | CRK isoform 1. | 0.981 |
| ABL1 | CRKL | ENSPPYP00000022265 | ENSPPYP00000024295 | Tyrosine-protein kinase. | CRKL isoform 1. | 0.994 |
| ABL1 | EGFR | ENSPPYP00000022265 | ENSPPYP00000019671 | Tyrosine-protein kinase. | Receptor protein-tyrosine kinase. | 0.831 |
| ABL1 | GRB2 | ENSPPYP00000022265 | ENSPPYP00000009686 | Tyrosine-protein kinase. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.992 |
| ABL1 | PIK3R1 | ENSPPYP00000022265 | ENSPPYP00000017341 | Tyrosine-protein kinase. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.869 |
| ABL1 | VAV1 | ENSPPYP00000022265 | ENSPPYP00000010613 | Tyrosine-protein kinase. | VAV1 isoform 2. | 0.797 |
| CBL | ABL1 | ENSPPYP00000004540 | ENSPPYP00000022265 | Cbl proto-oncogene. | Tyrosine-protein kinase. | 0.993 |
| CBL | CRK | ENSPPYP00000004540 | ENSPPYP00000008754 | Cbl proto-oncogene. | CRK isoform 1. | 0.994 |
| CBL | CRKL | ENSPPYP00000004540 | ENSPPYP00000024295 | Cbl proto-oncogene. | CRKL isoform 1. | 0.997 |
| CBL | EGFR | ENSPPYP00000004540 | ENSPPYP00000019671 | Cbl proto-oncogene. | Receptor protein-tyrosine kinase. | 0.999 |
| CBL | GRB2 | ENSPPYP00000004540 | ENSPPYP00000009686 | Cbl proto-oncogene. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.996 |
| CBL | MET | ENSPPYP00000004540 | ENSPPYP00000020106 | Cbl proto-oncogene. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.995 |
| CBL | PIK3R1 | ENSPPYP00000004540 | ENSPPYP00000017341 | Cbl proto-oncogene. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.986 |
| CBL | SH2B2 | ENSPPYP00000004540 | ENSPPYP00000019567 | Cbl proto-oncogene. | SH2B2 isoform 1. | 0.990 |
| CBL | SH3KBP1 | ENSPPYP00000004540 | ENSPPYP00000022571 | Cbl proto-oncogene. | SH3KBP1 isoform 1. | 0.994 |
| CBL | VAV1 | ENSPPYP00000004540 | ENSPPYP00000010613 | Cbl proto-oncogene. | VAV1 isoform 2. | 0.995 |
| CRK | ABL1 | ENSPPYP00000008754 | ENSPPYP00000022265 | CRK isoform 1. | Tyrosine-protein kinase. | 0.981 |
| CRK | CBL | ENSPPYP00000008754 | ENSPPYP00000004540 | CRK isoform 1. | Cbl proto-oncogene. | 0.994 |
| CRK | CRKL | ENSPPYP00000008754 | ENSPPYP00000024295 | CRK isoform 1. | CRKL isoform 1. | 0.991 |
