| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHFR | COPS2 | ENSPPYP00000005869 | ENSPPYP00000007321 | E3 ubiquitin-protein ligase CHFR; E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys- 48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURK [...] | COP9 signalosome subunit 2. | 0.485 |
| CHFR | SLC29A2 | ENSPPYP00000005869 | ENSPPYP00000004688 | E3 ubiquitin-protein ligase CHFR; E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys- 48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURK [...] | Solute carrier family 29 member 2. | 0.466 |
| CHFR | TBRG1 | ENSPPYP00000005869 | ENSPPYP00000004590 | E3 ubiquitin-protein ligase CHFR; E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys- 48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURK [...] | Transforming growth factor beta regulator 1. | 0.633 |
| COPS2 | CHFR | ENSPPYP00000007321 | ENSPPYP00000005869 | COP9 signalosome subunit 2. | E3 ubiquitin-protein ligase CHFR; E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys- 48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURK [...] | 0.485 |
| COPS2 | FBXO3 | ENSPPYP00000007321 | ENSPPYP00000003870 | COP9 signalosome subunit 2. | F-box protein 3. | 0.512 |
| COPS2 | KNTC1 | ENSPPYP00000007321 | ENSPPYP00000005777 | COP9 signalosome subunit 2. | KNTC1 isoform 1. | 0.514 |
| COPS2 | RBBP5 | ENSPPYP00000007321 | ENSPPYP00000000338 | COP9 signalosome subunit 2. | RBBP5 isoform 2. | 0.535 |
| COPS2 | SLC29A2 | ENSPPYP00000007321 | ENSPPYP00000004688 | COP9 signalosome subunit 2. | Solute carrier family 29 member 2. | 0.568 |
| COPS2 | TBRG1 | ENSPPYP00000007321 | ENSPPYP00000004590 | COP9 signalosome subunit 2. | Transforming growth factor beta regulator 1. | 0.713 |
| FBXO3 | COPS2 | ENSPPYP00000003870 | ENSPPYP00000007321 | F-box protein 3. | COP9 signalosome subunit 2. | 0.512 |
| FBXO3 | KNTC1 | ENSPPYP00000003870 | ENSPPYP00000005777 | F-box protein 3. | KNTC1 isoform 1. | 0.509 |
| FBXO3 | SLC29A2 | ENSPPYP00000003870 | ENSPPYP00000004688 | F-box protein 3. | Solute carrier family 29 member 2. | 0.511 |
| FBXO3 | TBRG1 | ENSPPYP00000003870 | ENSPPYP00000004590 | F-box protein 3. | Transforming growth factor beta regulator 1. | 0.656 |
| GARNL3 | TBRG1 | ENSPPYP00000021985 | ENSPPYP00000004590 | GARNL3 isoform 1. | Transforming growth factor beta regulator 1. | 0.618 |
| GARNL3 | TRAPPC10 | ENSPPYP00000021985 | ENSPPYP00000012814 | GARNL3 isoform 1. | TRAPPC10 isoform 2. | 0.617 |
| GDPD5 | TBRG1 | ENSPPYP00000004217 | ENSPPYP00000004590 | GDPD5 isoform 1. | Transforming growth factor beta regulator 1. | 0.633 |
| GDPD5 | TSKU | ENSPPYP00000004217 | ENSPPYP00000004230 | GDPD5 isoform 1. | Tsukushi, small leucine rich proteoglycan. | 0.530 |
| KNTC1 | COPS2 | ENSPPYP00000005777 | ENSPPYP00000007321 | KNTC1 isoform 1. | COP9 signalosome subunit 2. | 0.514 |
| KNTC1 | FBXO3 | ENSPPYP00000005777 | ENSPPYP00000003870 | KNTC1 isoform 1. | F-box protein 3. | 0.509 |
| KNTC1 | SLC29A2 | ENSPPYP00000005777 | ENSPPYP00000004688 | KNTC1 isoform 1. | Solute carrier family 29 member 2. | 0.528 |
