CR201_G0005896 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0005896	GARNL3	ENSPPYP00000004703	ENSPPYP00000021985	GRAMD1B isoform 5.	GARNL3 isoform 1.	0.533
CR201_G0005896	GRAMD1A	ENSPPYP00000004703	ENSPPYP00000011024	GRAMD1B isoform 5.	GRAMD1A isoform 3.	0.761
CR201_G0005896	GRAMD1C	ENSPPYP00000004703	ENSPPYP00000015133	GRAMD1B isoform 5.	Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...]	0.790
CR201_G0005896	GRAMD2B	ENSPPYP00000004703	ENSPPYP00000017586	GRAMD1B isoform 5.	GRAM domain-containing protein 2B.	0.792
CR201_G0005896	HMX2	ENSPPYP00000004703	ENSPPYP00000003191	GRAMD1B isoform 5.	HMX2 isoform 1.	0.618
CR201_G0005896	HMX3	ENSPPYP00000004703	ENSPPYP00000003190	GRAMD1B isoform 5.	HMX3 isoform 1.	0.484
CR201_G0005896	HTR2C	ENSPPYP00000004703	ENSPPYP00000023110	GRAMD1B isoform 5.	HTR2C isoform 1.	0.950
CR201_G0005896	NYX	ENSPPYP00000004703	ENSPPYP00000022672	GRAMD1B isoform 5.	NYX isoform 1.	0.485
CR201_G0005896	TBRG1	ENSPPYP00000004703	ENSPPYP00000004590	GRAMD1B isoform 5.	Transforming growth factor beta regulator 1.	0.607
CR201_G0005896	TRAPPC10	ENSPPYP00000004703	ENSPPYP00000012814	GRAMD1B isoform 5.	TRAPPC10 isoform 2.	0.618
GARNL3	CR201_G0005896	ENSPPYP00000021985	ENSPPYP00000004703	GARNL3 isoform 1.	GRAMD1B isoform 5.	0.533
GARNL3	TBRG1	ENSPPYP00000021985	ENSPPYP00000004590	GARNL3 isoform 1.	Transforming growth factor beta regulator 1.	0.618
GARNL3	TRAPPC10	ENSPPYP00000021985	ENSPPYP00000012814	GARNL3 isoform 1.	TRAPPC10 isoform 2.	0.617
GRAMD1A	CR201_G0005896	ENSPPYP00000011024	ENSPPYP00000004703	GRAMD1A isoform 3.	GRAMD1B isoform 5.	0.761
GRAMD1A	GRAMD2B	ENSPPYP00000011024	ENSPPYP00000017586	GRAMD1A isoform 3.	GRAM domain-containing protein 2B.	0.544
GRAMD1C	CR201_G0005896	ENSPPYP00000015133	ENSPPYP00000004703	Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...]	GRAMD1B isoform 5.	0.790
GRAMD1C	GRAMD2B	ENSPPYP00000015133	ENSPPYP00000017586	Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...]	GRAM domain-containing protein 2B.	0.829
GRAMD2B	CR201_G0005896	ENSPPYP00000017586	ENSPPYP00000004703	GRAM domain-containing protein 2B.	GRAMD1B isoform 5.	0.792
GRAMD2B	GRAMD1A	ENSPPYP00000017586	ENSPPYP00000011024	GRAM domain-containing protein 2B.	GRAMD1A isoform 3.	0.544
GRAMD2B	GRAMD1C	ENSPPYP00000017586	ENSPPYP00000015133	GRAM domain-containing protein 2B.	Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...]	0.829